Detalhe da pesquisa
1.
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry.
J Am Chem Soc
; 145(40): 21937-21944, 2023 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37767920
2.
Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader.
Angew Chem Int Ed Engl
; 62(18): e202302364, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36898968
3.
Approaches toward Atropisomerically Stable and Conformationally Pure Diarylamines.
J Org Chem
; 87(10): 6760-6768, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35486501
4.
Redox-Responsive H-Bonding: Amplifying the Effect of Electron Transfer Using Proton-Coupled Electron Transfer.
J Am Chem Soc
; 142(41): 17271-17276, 2020 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32981317
5.
Catalytic Atroposelective Synthesis of N-Aryl Quinoid Compounds.
J Am Chem Soc
; 142(5): 2198-2203, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31944689
6.
Discovery of cyclic guanidine-linked sulfonamides as inhibitors of LMTK3 kinase.
Bioorg Med Chem Lett
; 30(9): 127108, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32192797
7.
Controlling Ibrutinib's Conformations about Its Heterobiaryl Axis to Increase BTK Selectivity.
ACS Med Chem Lett
; 14(3): 305-311, 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923918
8.
Development and Utility of a PAK1-Selective Degrader.
J Med Chem
; 65(23): 15627-15641, 2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36416208
9.
Leveraging Atropisomerism to Obtain a Selective Inhibitor of RET Kinase with Secondary Activities toward EGFR Mutants.
ACS Chem Biol
; 14(9): 1930-1939, 2019 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31424197
10.
Atropisomerism in medicinal chemistry: challenges and opportunities.
Future Med Chem
; 10(4): 409-422, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29380622
11.
Enantioselective Synthesis of Pyrrolopyrimidine Scaffolds through Cation-Directed Nucleophilic Aromatic Substitution.
Org Lett
; 20(7): 2037-2041, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29561161
12.
Towards a Catalytic Atroposelective Synthesis of Diaryl Ethers via C(sp 2)-H Alkylation Using Nitroalkanes.
Synlett
; 29(16): 2155-2160, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31178629
13.
A conjugate Lewis base-Brønsted acid catalyst for the sulfenylation of nitrogen containing heterocycles under mild conditions.
Chem Commun (Camb)
; 53(9): 1494-1497, 2017 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28084476
14.
Leveraging conformational control about a potential atropisomeric axis as a strategy in medical chemistry.
Future Med Chem
; 13(5): 443-446, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472413