Detalhe da pesquisa
1.
Peripheral Aß acts as a negative modulator of insulin secretion.
Proc Natl Acad Sci U S A
; 119(12): e2117723119, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35290109
2.
Peripheral administration of nanomicelle-encapsulated anti-Aß oligomer fragment antibody reduces various toxic Aß species in the brain.
J Nanobiotechnology
; 21(1): 36, 2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36721182
3.
Nasal Rifampicin Improves Cognition in a Mouse Model of Dementia with Lewy Bodies by Reducing α-Synuclein Oligomers.
Int J Mol Sci
; 22(16)2021 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445158
4.
Fluorine-19 Magnetic Resonance Imaging for Detection of Amyloid ß Oligomers Using a Keto Form of Curcumin Derivative in a Mouse Model of Alzheimer's Disease.
Molecules
; 26(5)2021 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33806326
5.
Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain.
J Neurosci
; 39(34): 6781-6797, 2019 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31235644
6.
APP Osaka Mutation in Familial Alzheimer's Disease-Its Discovery, Phenotypes, and Mechanism of Recessive Inheritance.
Int J Mol Sci
; 21(4)2020 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32093100
7.
Heavy Tau Burden with Subtle Amyloid ß Accumulation in the Cerebral Cortex and Cerebellum in a Case of Familial Alzheimer's Disease with APP Osaka Mutation.
Int J Mol Sci
; 21(12)2020 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32580499
8.
Rifampicin is a candidate preventive medicine against amyloid-ß and tau oligomers.
Brain
; 139(Pt 5): 1568-86, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27020329
9.
Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease.
Neuropathology
; 37(6): 495-501, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28731225
10.
Neurodegenerative disorder FTDP-17-related tau intron 10 +16C â T mutation increases tau exon 10 splicing and causes tauopathy in transgenic mice.
Am J Pathol
; 183(1): 211-25, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23680655
11.
Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice.
Acta Neuropathol
; 127(5): 685-98, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24531886
12.
Hawaiian native herb Mamaki prevents dementia by ameliorating neuropathology and repairing neurons in four different mouse models of neurodegenerative diseases.
Geroscience
; 46(2): 1971-1987, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783918
13.
The microtubule-dynamin binding inhibitor peptide PHDP5 rescues spatial learning and memory deficits in Alzheimer's disease model mice.
Brain Res
; 1838: 148987, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38718851
14.
Investigating the efficacy of nasal administration for delivering magnetic nanoparticles into the brain for magnetic particle imaging.
J Control Release
; 367: 515-521, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38237689
15.
The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid ß toxicity via its impaired cholesterol efflux.
J Neurosci Res
; 91(12): 1541-50, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24105984
16.
In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders.
J Neurosci
; 31(12): 4720-30, 2011 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21430171
17.
Nasal Rifampicin Halts the Progression of Tauopathy by Inhibiting Tau Oligomer Propagation in Alzheimer Brain Extract-Injected Mice.
Biomedicines
; 10(2)2022 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35203506
18.
C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice.
Biomedicines
; 10(5)2022 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35625816
19.
A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.
J Neurosci
; 30(14): 4845-56, 2010 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371804
20.
Intraneuronal amyloid ß oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo.
J Neurosci Res
; 89(7): 1031-42, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21488093