Detalhe da pesquisa
1.
On the Race to Starvation: How Do Bacteria Survive High Doses of Antibiotics?
Mol Cell
; 68(6): 1019-1021, 2017 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29272702
2.
Kinetic Barrier to Enzyme Inhibition Is Manipulated by Dynamical Local Interactions in E. coli DHFR.
J Chem Inf Model
; 63(15): 4839-4849, 2023 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37491825
3.
The Antibiotic Efflux Protein TolC Is a Highly Evolvable Target under Colicin E1 or TLS Phage Selection.
Mol Biol Evol
; 38(10): 4493-4504, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34175926
4.
Rapid ultrasensitive detection platform for antimicrobial susceptibility testing.
PLoS Biol
; 17(5): e3000291, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31145726
5.
High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection.
Mol Biol Evol
; 36(7): 1533-1550, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30982891
6.
Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy.
PLoS Biol
; 14(9): e1002552, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27631336
7.
Quantifying the Determinants of Evolutionary Dynamics Leading to Drug Resistance.
PLoS Biol
; 13(11): e1002299, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26581035
8.
Fighting against evolution of antibiotic resistance by utilizing evolvable antimicrobial drugs.
Curr Genet
; 63(6): 973-976, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28497241
9.
Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance.
Phys Chem Chem Phys
; 19(18): 11416-11428, 2017 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28422217
10.
Strength of selection pressure is an important parameter contributing to the complexity of antibiotic resistance evolution.
Mol Biol Evol
; 31(9): 2387-401, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24962091
11.
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance.
Cell Host Microbe
; 32(3): 396-410.e6, 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38359828
12.
Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance.
bioRxiv
; 2023 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711614
13.
Why kinesin is so processive.
Proc Natl Acad Sci U S A
; 106(31): 12717-22, 2009 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19617538
14.
Myosin VI undergoes a 180 degrees power stroke implying an uncoupling of the front lever arm.
Proc Natl Acad Sci U S A
; 106(43): 18255-60, 2009 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19828438
15.
Label-Free Optical Detection of Pathogenic Bacteria and Fungi at Extremely Low Cell Densities for Rapid Antibiotic Susceptibility Testing.
Front Bioeng Biotechnol
; 10: 884200, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35845405
16.
A trimethoprim derivative impedes antibiotic resistance evolution.
Nat Commun
; 12(1): 2949, 2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011959
17.
Non-antibiotic Small-Molecule Regulation of DHFR-Based Destabilizing Domains In Vivo.
Mol Ther Methods Clin Dev
; 15: 27-39, 2019 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31649953
18.
Polarization effect on position accuracy of fluorophore localization.
Opt Express
; 14(18): 8111-20, 2006 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19529183
19.
Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells.
Nat Commun
; 7: 11641, 2016 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189321
20.
Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes.
Nat Commun
; 6: 7385, 2015 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26060115