Detalhe da pesquisa
1.
Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients.
Hum Mol Genet
; 26(6): 1087-1103, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28087734
2.
Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading.
Proc Natl Acad Sci U S A
; 113(9): E1206-15, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884195
3.
The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity.
Hum Mol Genet
; 23(21): 5615-29, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895406
4.
Fast flow microfluidics and single-molecule fluorescence for the rapid characterization of α-synuclein oligomers.
Anal Chem
; 87(17): 8818-26, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26258431
5.
Alpha-synuclein pore forming activity upon membrane association.
Biochim Biophys Acta
; 1818(11): 2876-83, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22820150
6.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Nat Commun
; 14(1): 603, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36746939
7.
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function.
Sci Adv
; 9(1): eade1694, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36608116
8.
A glance at post-translational modifications of human thyroglobulin: potential impact on function and pathogenesis.
Eur Thyroid J
; 11(3)2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35544053
9.
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity.
Nat Neurosci
; 25(9): 1134-1148, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36042314
10.
ClC-2-like Chloride Current Alterations in a Cell Model of Spinal and Bulbar Muscular Atrophy, a Polyglutamine Disease.
J Mol Neurosci
; 71(3): 662-674, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32856205
11.
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
Cell Rep
; 35(2): 108980, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852844
12.
Pharmacological inactivation of the prion protein by targeting a folding intermediate.
Commun Biol
; 4(1): 62, 2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33437023
13.
Dopamine quinones interact with alpha-synuclein to form unstructured adducts.
Biochem Biophys Res Commun
; 394(2): 424-8, 2010 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20226175
14.
Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers.
Chembiochem
; 10(1): 176-83, 2009 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19067456
15.
Shedding light on aberrant interactions - a review of modern tools for studying protein aggregates.
FEBS J
; 285(19): 3604-3630, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29453901
16.
Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers.
Cell Rep
; 23(12): 3492-3500, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29924993
17.
Quantifying Co-Oligomer Formation by α-Synuclein.
ACS Nano
; 12(11): 10855-10866, 2018 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30371053
18.
Altered ionic currents and amelioration by IGF-1 and PACAP in motoneuron-derived cells modelling SBMA.
Biophys Chem
; 229: 68-76, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28511915
19.
Author Correction: Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity.
Nat Neurosci
; 25(11): 1582, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36261654
20.
Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein.
Sci Rep
; 6: 33928, 2016 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27671749