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Alzheimers Dement ; 19(11): 5264-5283, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37392199

RESUMO

In Lewy body dementia (LBD), disturbances of sleep and/or arousal including insomnia, excessive daytime sleepiness, rapid eye movement (REM) sleep behavior disorder, obstructive sleep apnea, and restless leg syndrome are common. These disorders can each exert a significant negative impact on both patient and caregiver quality of life; however, their etiology is poorly understood. Little guidance is available for assessing and managing sleep disorders in LBD, and they remain under-diagnosed and under-treated. This review aims to (1) describe the specific sleep disorders which occur in LBD, considering their putative or potential mechanisms; (2) describe the history and diagnostic process for these disorders in LBD; and (3) summarize current evidence for their management in LBD and consider some of the ongoing and unanswered questions in this field and future research directions.


Assuntos
Doença por Corpos de Lewy , Transtorno do Comportamento do Sono REM , Transtornos do Sono-Vigília , Humanos , Doença por Corpos de Lewy/diagnóstico , Relevância Clínica , Qualidade de Vida , Sono , Transtornos do Sono-Vigília/etiologia
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