Detalhe da pesquisa
1.
Structural and functional complexity of HSP90 in cellular homeostasis and disease.
Nat Rev Mol Cell Biol
; 24(11): 797-815, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524848
2.
A Single-Arm, Open-Label Phase II Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma.
Oncologist
; 28(10): 919-e972, 2023 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37279797
3.
Efficacy and exploratory biomarker analysis of entinostat plus exemestane in advanced or recurrent breast cancer: phase II randomized controlled trial.
Jpn J Clin Oncol
; 53(1): 4-15, 2023 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36398439
4.
A phase II trial of the super-enhancer inhibitor Minnelide™ in advanced refractory adenosquamous carcinoma of the pancreas.
Future Oncol
; 18(20): 2475-2481, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35535581
5.
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.
Mol Cell
; 53(2): 317-29, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24462205
6.
Cabozantinib plus docetaxel and prednisone in metastatic castration-resistant prostate cancer.
BJU Int
; 127(4): 435-444, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32969563
7.
A phase 1 study of entinostat in children and adolescents with recurrent or refractory solid tumors, including CNS tumors: Trial ADVL1513, Pediatric Early Phase-Clinical Trial Network (PEP-CTN).
Pediatr Blood Cancer
; 68(4): e28892, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33438318
8.
Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma: an open-label, single-centre, phase 2 trial.
Lancet Oncol
; 21(8): 1099-1109, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645282
9.
A Phase II Single Arm Pilot Study of the CHK1 Inhibitor Prexasertib (LY2606368) in BRCA Wild-Type, Advanced Triple-Negative Breast Cancer.
Oncologist
; 25(12): 1013-e1824, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32510664
10.
Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
Mol Cell
; 47(3): 434-43, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22727666
11.
RRx-001 followed by platinum plus etoposide in patients with previously treated small-cell lung cancer.
Br J Cancer
; 121(3): 211-217, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31231122
12.
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.
Mol Cell
; 41(6): 672-81, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21419342
13.
Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study.
Lancet Oncol
; 19(2): 207-215, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29361470
14.
Cancer vaccine strategies: translation from mice to human clinical trials.
Cancer Immunol Immunother
; 67(12): 1863-1869, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29143114
15.
Phase I trial of belinostat with cisplatin and etoposide in advanced solid tumors, with a focus on neuroendocrine and small cell cancers of the lung.
Anticancer Drugs
; 29(5): 457-465, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420340
16.
Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy.
BMC Gastroenterol
; 18(1): 94, 2018 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29933761
17.
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.
Mol Cell
; 37(3): 333-43, 2010 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20159553
18.
Immunotherapy: a new treatment paradigm in bladder cancer.
Curr Opin Oncol
; 29(3): 184-195, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28306559
19.
Lack of Impact of Robotic Assisted Laparoscopic Radical Prostatectomy on Intraoperative Levels of Prostate Cancer Circulating Tumor Cells.
J Urol
; 195(4 Pt 1): 1136-42, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26581128
20.
Phase II trial of docetaxel, bevacizumab, lenalidomide and prednisone in patients with metastatic castration-resistant prostate cancer.
BJU Int
; 118(4): 590-7, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26780387