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1.
Eur J Appl Physiol ; 124(3): 881-896, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37776346

RESUMO

PURPOSE: To determine the recovery kinetics of performance and exercise-induced muscle damage following different sprint-training protocols. METHODS: In a crossover design, ten male and female athletes (20.6 ± 2.4 years) performed 2 × (3 × 20 m: 2 min rest) and 1× (3 × 30 m: 3 min rest) of: (a) unresisted sprints (UST), (b) resisted sprints with 10% of body mass (BM) load (RST10), (c) resisted sprints with 20% BM load (RST20), against a control trial (no-training). RESULTS: Blood lactate (mmol/L) increased post-training versus pre-training in all sprint-training trials (6.7 ± 2.4 vs 1.2 ± 0.2, 5.6 ± 2.4 vs 1.3 ± 0.3, 7.3 ± 2.7 vs 1.2 ± 0.3, in UST, RST10, RST20, respectively), as did creatine kinase (U/L) 24 h, 48 h and 72 h post-training (UST: 251 ± 173, 238 ± 154, 209 ± 115 vs 155 ± 9, RST10: 252 ± 134, 240 ± 83, 218 ± 103 vs 164 ± 106; RST20: 237 ± 133, 323 ± 303, 262 ± 184 vs 179 ± 106, respectively). DOMS of knee-extensors (KE) and knee-flexors (KF) increased post-training up to 72 h in all sprint-training trials versus pre-training (ranging from 1.6 ± 1.3 to 3.8 ± 2.8 vs 1.0 ± 0, respectively). Eccentric torque (N m) of the KE of the non-dominant limb, decreased 24 h post-training versus pre-training in all sprint-training trials (UST: 249 ± 49 vs 266 ± 54; RST10: 229 ± 52 vs 273 ± 72; RST20: 253 ± 6 vs 262 ± 56), as did that of the KF of the dominant limb (UST: 135 ± 29 vs 144 ± 26; RST10: 130 ± 29 vs 140 ± 25; RST20: 139 ± 33 vs 142 ± 26). 10-m sprint-time (s) increased 48 h post-training versus pre-training (1.81 ± 0.15 vs 1.77 ± 0.11), and 30-m sprint-time increased 24 h, 48 h, 72 h post-training versus pre-training (4.35 ± 0.36, 4.40 ± 0.44, 4.33 ± 0.41 vs 4.21 ± 0.34, respectively), only in RST20. CONCLUSIONS: Unresisted and resisted sprint-training induces prolonged reduction of muscle strength (24 h), and sprinting performance (72 h), associated with prolonged increase of DOMS and CK (72 h).


Assuntos
Desempenho Atlético , Treinamento Resistido , Humanos , Masculino , Feminino , Desempenho Atlético/fisiologia , Treinamento Resistido/métodos , Atletas , Modalidades de Fisioterapia , Joelho
2.
J Sports Sci ; 41(13): 1326-1335, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37864292

RESUMO

The present study compared the effect of 75 vs 150 vs 300 intensity-matched eccentric contractions on muscle damage and performance recovery kinetics. Ten healthy males participated in a randomized, cross-over study consisted of 4 experimental trials (ECC75, ECC150, ECC300 and Control - no exercise) with a 4-week washout period in-between. Performance and muscle damage, inflammatory and oxidative stress markers were evaluated at baseline, post-exercise, 24, 48 and 192 hours following each exercise protocol. Concentric and eccentric peak torque decreased similarly in ECC150 and ECC300 during the first 48 h of recovery (p < 0.05) but remained unaffected in ECC75. Countermovement jump indices decreased post-exercise and at 24 h in ECC150 and ECC300, with ECC300 inducing a more pronounced reduction (p < 0.05). Creatine kinase increased until 48 h of recovery in all trials and remained elevated up to 192 h only in ECC300 (p < 0.05). Delayed onset of muscle soreness increased, and knee-joint range of motion decreased in a volume-dependent manner during the first 48 h (p < 0.05). Likewise, a volume-dependent decline of glutathione and a rise of protein carbonyls was observed during the first 48 h of recovery (p < 0.05). Collectively, our results indicate that muscle damage and performance recovery following eccentric exercise is volume dependent, at least in lower limbs.


Assuntos
Exercício Físico , Mialgia , Masculino , Humanos , Estudos Cross-Over , Exercício Físico/fisiologia , Amplitude de Movimento Articular , Articulação do Joelho
3.
Sensors (Basel) ; 23(4)2023 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-36850945

RESUMO

This systematic review documents the protocol characteristics of studies that used neuromuscular electrical stimulation protocols (NMES) on the plantar flexors [through triceps surae (TS) or tibial nerve (TN) stimulation] to stimulate afferent pathways. The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement, was registered to PROSPERO (ID: CRD42022345194) and was funded by the Greek General Secretariat for Research and Technology (ERA-NET NEURON JTC 2020). Included were original research articles on healthy adults, with NMES interventions applied on TN or TS or both. Four databases (Cochrane Library, PubMed, Scopus, and Web of Science) were systematically searched, in addition to a manual search using the citations of included studies. Quality assessment was conducted on 32 eligible studies by estimating the risk of bias with the checklist of the Effective Public Health Practice Project Quality Assessment Tool. Eighty-seven protocols were analyzed, with descriptive statistics. Compared to TS, TN stimulation has been reported in a wider range of frequencies (5-100, vs. 20-200 Hz) and normalization methods for the contraction intensity. The pulse duration ranged from 0.2 to 1 ms for both TS and TN protocols. It is concluded that with increasing popularity of NMES protocols in intervention and rehabilitation, future studies may use a wider range of stimulation attributes, to stimulate motor neurons via afferent pathways, but, on the other hand, additional studies may explore new protocols, targeting for more optimal effectiveness. Furthermore, future studies should consider methodological issues, such as stimulation efficacy (e.g., positioning over the motor point) and reporting of level of discomfort during the application of NMES protocols to reduce the inherent variability of the results.


Assuntos
Perna (Membro) , Nervo Tibial , Adulto , Animais , Humanos , Vias Aferentes , Lista de Checagem , Estimulação Elétrica , Peixes
4.
Medicina (Kaunas) ; 59(8)2023 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-37629698

RESUMO

The aim of the present study is to examine the acute effects of a specially designed musicokinetic (MSK) program for patients with Parkinson's disease (PD) on (a) anxiety levels, (b) select kinematic and kinetic parameters, and (c) frontal cortex hemodynamic responses, during gait initiation and steady-state walking. Methods: This is a blind cross-over randomized control trial (RCT) in which 13 volunteers with PD will attend a 45 min MSK program under the following conditions: (a) a synchronous learning format and (b) an asynchronous remote video-based format. Changes in gait biomechanics and frontal cortex hemodynamic responses will be examined using a 10-camera 3D motion analysis (Vicon T-series, Oxford, UK), and a functional near-infrared spectroscopy (f-NIRS-Portalite, Artinis NL) system, respectively, while anxiety levels will be evaluated using the Hamilton Anxiety Rating Scale. Expected results: Guided by the rules of music, where periodicity is distinct, our specially designed MSK program may eventually be beneficial in improving motor difficulties and, hence, reducing anxiety. The combined implementation of f-NIRS in parallel with 3D gait analysis has yet to be evaluated in Parkinsonian patients following a MSK intervention. It is expected that the aforementioned intervention, through better rhythmicity, may improve the automatization of motor control, gait kinematics, and kinetics-supported by decreased frontal cortex hemodynamic activity-which may be linked to reduced anxiety levels.


Assuntos
Doença de Parkinson , Humanos , Doença de Parkinson/terapia , Movimento , Ansiedade , Transtornos de Ansiedade , Fenômenos Biomecânicos
5.
Med Probl Perform Art ; 35(4): 202-207, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33257922

RESUMO

AIMS: Although the significance of upper-body posture in relation to piano performance has often been highlighted, the role of experience remains unclear. The aim of this study was to examine selected upper body posture parameters in adolescent piano students of different performance level (beginners vs advanced). METHODS: Thirteen (13) adolescent piano students (14.7±0.5 yrs; 7 beginners and 6 advanced) volunteered. They all performed two specific major scales (G-major and E-major) in five octaves in two predetermined different tempi (slow and fast). An upper body biomechanical model consisting of 27 reflective markers was applied on specific bony landmarks. A 10-T camera Vicon system running Nexus 2 was employed to capture upper body motion--a) sway of the trunk in relation to the instrument, b) finger/hand sway over the keyboard, c) overall hand movement, and d) spinal angles--at selected moments of four different performances. RESULTS: Beginners demonstrated more trunk sway than their advanced counterparts (p<0.05), more finger/hand sway (p<0.05), more overall hand movement (p<0.05), and more flexed spinal angles at the start of their performance (p<0.05). Most of these differences appeared in the G-fast performances, whereas the G-slow equivalents revealed no differences. CONCLUSION: Less-experienced piano players are characterized by more movement in their trunk posture and more upper limb activity than their more advanced colleagues. Future research should examine whether interventional programs designed to alter upper-body posture would have beneficial effects in piano performance.


Assuntos
Mãos , Postura , Adolescente , Fenômenos Biomecânicos , Estudos Transversais , Humanos , Movimento , Tronco
6.
Scand J Med Sci Sports ; 29(3): 380-392, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30468526

RESUMO

Studies examining acute, high-speed movement performance enhancement following intense muscular contractions (frequently called "post-activation potentiation"; PAP) often impose a limited warm-up, compromizing external validity. In the present study, the effects on countermovement vertical jump (CMJ) performance of back squat exercises performed with or without elastic bands during warm-up were compared. After familiarization, fifteen active men visited the laboratory on two occasions under randomized, counterbalanced experimental squat warm-up conditions: (a) free-weight resistance (FWR) and (b) variable resistance (VR). After completing a comprehensive task-specific warm-up, three maximal CMJs were performed followed by three back squat repetitions completed at 85% of 1-RM using either FWR or VR Three CMJs were then performed 30 seconds, 4 minutes, 8 minutes, and 12 minutes later. During CMJ trials, hip, knee, and ankle joint kinematics, ground reaction force data and vastus medialis, vastus lateralis, and gluteus maximus electromyograms (EMG) were recorded simultaneously using 3D motion analysis, force platform, and EMG techniques, respectively. No change in any variable occurred after FWR (P > 0.05). Significant increases (P < 0.05) were detected at all time points following VR in CMJ height (5.3%-6.5%), peak power (4.4%-5.9%), rate of force development (12.9%-19.1%), peak concentric knee angular velocity (3.1%-4.1%), and mean concentric vastus lateralis EMG activity (27.5%-33.4%). The lack of effect of the free-weight conditioning contractions suggests that the comprehensive task-specific warm-up routine mitigated any further performance augmentation. However, the improved CMJ performance following the use of elastic bands is indicative that specific alterations in force-time properties of warm-up exercises may further improve performance.


Assuntos
Músculo Esquelético/fisiologia , Postura , Exercício de Aquecimento , Levantamento de Peso/fisiologia , Articulação do Tornozelo , Desempenho Atlético/fisiologia , Fenômenos Biomecânicos , Estudos Cross-Over , Eletromiografia , Articulação do Quadril , Humanos , Articulação do Joelho , Masculino , Adulto Jovem
7.
J Sports Sci ; 36(2): 131-139, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28282755

RESUMO

The study examined the differences between boys and adults after an intense stretch-shortening cycle fatigue protocol on neuromechanical parameters of the lower limb. Thirteen boys (9-11 years old) and 13 adult men (22-28 years old) were tested for maximal isometric voluntary knee extension torque and drop jump (DJ) performance from 30 cm before and immediately after a fatigue protocol, consisted of 10 × 10 maximum effort vertical jumps. Three-dimensional kinematics, kinetics and electromyographic (EMG) parameters of the lower extremities muscles were recorded during DJs before and after the fatigue test. The results indicated that reduction in maximal isometric torque and jumping performance was significantly higher in adults compared to boys. Vertical ground reaction forces, contact time and maximum knee flexion increased in a greater extend in adults than in boys. In addition, preactivation, EMG agonist activity, knee joint stiffness and stretch reflex decreased more in adults than in boys at all the examined phases of jumping tasks. It is concluded that employed fatigue protocol induced acute reduction in performance and altered motor control during jumping in both age groups. However, the differences in the level of fatigue between the 2 groups could be attributed to neuromuscular, mechanical and kinematic parameters observed between groups.


Assuntos
Extremidade Inferior/fisiologia , Fadiga Muscular/fisiologia , Músculo Esquelético/fisiologia , Exercício Pliométrico , Adulto , Fatores Etários , Fenômenos Biomecânicos , Criança , Eletromiografia , Humanos , Cinética , Extremidade Inferior/inervação , Masculino , Neurônios Motores/fisiologia , Músculo Esquelético/inervação , Adulto Jovem
8.
J Funct Morphol Kinesiol ; 9(2)2024 May 21.
Artigo em Inglês | MEDLINE | ID: mdl-38804454

RESUMO

The game of soccer is complex and unpredictable, demanding multifaceted strategies for success. Performance analysis has evolved, focusing on key performance indicators (KPIs) to determine the factors that most significantly influence a team's success or failure during matches. Traditional performance analysis methods have emphasized quantifiable data like physical exertion and basic play events but often neglected the subtler tactical dimensions that could significantly impact game outcomes. This study aimed to fill the gap in the current literature by creating a comprehensive framework that incorporates tactical situations as KPIs. The objective was to examine whether specific playing styles adopted by teams in various tactical situations and phases of the game could predict the outcome of matches. A dataset comprising all First Division Championship matches from 11 different European countries for the 2021-2022 season was analyzed. Variables representing tactical situations were correlated with match outcomes using a Generalized Estimating Equation framework. The model was specified with a binomial distribution and a logit link function. Statistical significance was determined using Wald χ2 tests with a significance level set at p < 0.05. The study's findings revealed that possession style, counterattacking during offensive transitions, and a balanced aggressive defensive strategy significantly increase a team's chances of victory. It also showed that successful teams tend to focus on central attacks, minimize crossing, and execute strategic plays that lead to final attempts on goal with minimal ball possession. The above findings demonstrate that adopting certain tactical approaches significantly influences soccer match outcomes, highlighting the importance of considering tactical aspects as KPIs.

9.
J Sports Sci ; 31(3): 288-98, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23046390

RESUMO

This study investigated the effects of knee localised muscle damage on running kinematics at varying speeds. Nineteen young women (23.2 ± 2.8 years; 164 ± 8 cm; 53.6 ± 5.4 kg), performed a maximal eccentric muscle damage protocol (5 × 15) of the knee extensors and flexors of both legs at 60 rad · s(-1). Lower body kinematics was assessed during level running on a treadmill at three speeds pre- and 48 h after. Evaluated muscle damage indices included isometric torque, muscle soreness and serum creatine kinase activity. The results revealed that all indices changed significantly after exercise, indicating muscle injury. Step length decreased and stride frequency significantly increased 48 h post-exercise only at the fastest running speed (3 m · s(-1)). Support time and knee flexion at toe-off increased only at the preferred transition speed and 2.5 m · s(-1). Knee flexion at foot contact, pelvic tilt and obliquity significantly increased, whereas hip extension during stance-phase, knee flexion during swing-phase, as well as knee and ankle joints range of motion significantly decreased 48 h post-exercise at all speeds. In conclusion, the effects of eccentric exercise of both knee extensors and flexors on particular tempo-spatial parameters and knee kinematics of running are speed-dependent. However, several pelvic and lower joint kinematics present similar behaviour at the three running speeds examined. These findings provide new insights into how running kinematics at different speeds are adapted to compensate for the impaired function of the knee musculature following muscle damage.


Assuntos
Exercício Físico/fisiologia , Articulação do Joelho , Joelho , Perna (Membro) , Músculo Esquelético/lesões , Corrida/fisiologia , Análise e Desempenho de Tarefas , Adulto , Fenômenos Biomecânicos , Creatina Quinase/sangue , Feminino , Marcha , Humanos , Contração Muscular , Dor , Pelve , Amplitude de Movimento Articular , Torque , Adulto Jovem
10.
J Funct Morphol Kinesiol ; 8(2)2023 May 04.
Artigo em Inglês | MEDLINE | ID: mdl-37218851

RESUMO

The present study aimed to identify the impact of social distancing measures on adolescents' physical activity (PA) levels and well-being during the implementation of COVID-19 restrictive measures. There were 438 participants (207 boys and 231 girls), aged 12 to 15 years old (M = 13.5, SD = 0.55). They completed online questionnaires on well-being and PA in three waves (December 2020, February 2021, and June 2021). Correlation analyses were conducted to examine the relationship between well-being and PA variables in the three measurements. Additionally, separate three-way repeated-measures ANOVAs were conducted to capture possible differences in students' moderate to vigorous physical activity (MVPA) levels, life satisfaction, and subjective vitality among the three measurements due to gender, age, and interaction between gender and age. A significant relation emerged between the MVPA variables and well-being. In all measurements, adolescents' PA levels did not meet the World Health Organization (WHO) recommendations of at least 60 min per day in MVPA. Students' MVPA levels, life satisfaction, and subjective vitality were significantly higher in the third measurement compared to the first and second ones. Moreover, significant differences emerged in life satisfaction and subjective vitality between boys and girls in the first and third measurements, respectively. The COVID-19 restrictions appeared to negatively influence adolescents' PA and well-being. Policymakers aimed at facilitating adolescents' well-being in a similar situation in the future should not adopt measures restricting the participation of adolescents in PA.

11.
J Funct Morphol Kinesiol ; 8(3)2023 Jul 26.
Artigo em Inglês | MEDLINE | ID: mdl-37606399

RESUMO

Identifying playing styles in football is highly valuable for achieving effective performance analysis. While there is extensive research on team styles, studies on individual player styles are still in their early stages. Thus, the aim of this systematic review was to provide a comprehensive overview of the existing literature on player styles and identify research areas required for further development, offering new directions for future research. Following the PRISMA guidelines for systematic reviews, we conducted a search using a specific strategy across four databases (PubMed, Scopus, Web of Science, and SPORTDiscus). Inclusion and exclusion criteria were applied to the initial search results, ultimately identifying twelve studies suitable for inclusion in this review. Through thematic analysis and qualitative evaluation of these studies, several key findings emerged: (a) a lack of a structured theoretical framework for player styles based on their positions within the team formation, (b) absence of studies investigating the influence of contextual variables on player styles, (c) methodological deficiencies observed in the reviewed studies, and (d) disparity in the objectives of sports science and data science studies. By identifying these gaps in the literature and presenting a structured framework for player styles (based on the compilation of all reported styles from the reviewed studies), this review aims to assist team stakeholders and provide guidance for future research endeavors.

12.
J Funct Morphol Kinesiol ; 8(2)2023 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-37092371

RESUMO

Identifying and measuring soccer playing styles is a very important step toward a more effective performance analysis. Exploring the different game styles that a team can adopt to enable a great performance remains under-researched. To address this challenge and identify new directions in future research in the area, this paper conducted a critical review of 40 research articles that met specific criteria. Following the 22-item Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines, this scoping review searched for literature on Google Scholar and Pub Med database. The descriptive and thematic analysis found that the objectives of the identified papers can be classified into three main categories (recognition and effectiveness of playing styles and contextual variables that affect them). Critically reviewing the studies, the paper concluded that: (i) factor analysis seems to be the best technique among inductive statistics; (ii) artificial intelligence (AI) opens new horizons in performance analysis, and (iii) there is a need for further research on the effectiveness of different playing styles, as well as on the impact of contextual variables on them.

13.
Nutrients ; 15(8)2023 Apr 18.
Artigo em Inglês | MEDLINE | ID: mdl-37111169

RESUMO

In sports nutrition, nitric oxide (NO•) precursors such as L-citrulline are widely used to enhance NO• bioavailability, which is considered an ergogenic aid. Our study aimed to examine the effect of short-term L-citrulline supplementation on respiratory muscles' performance, fatigue, and oxygenation in older adults. Fourteen healthy older males took 6 g of L-citrulline or a placebo for seven days in a double-blind crossover design. Pulmonary function via spirometry (i.e., forced expired volume in 1 s (FEV1), forced vital capacity (FVC), and their ratio)), fractional exhaled nitric oxide (NO•), maximal inspiratory pressure (MIP), rate of perceived exertion, and sternocleidomastoid muscle oxygenation (i.e., oxyhemoglobin (Δ[O2Hb]) and de-oxyhemoglobin (Δ[HHb]), total hemoglobin concentration (Δ[tHb]), and tissue saturation index (TSI%)) were evaluated at baseline, after seven days of L-citrulline supplementation, and after incremental resistive breathing to task failure of the respiratory muscles. The exhaled NO• value was only significantly increased after the supplementation (26% p < 0.001) in the L-citrulline condition. Pulmonary function, MIP, rate of perceived exertion, and sternocleidomastoid muscle oxygenation were not affected by the L-citrulline supplementation. In the present study, although short-term L-citrulline supplementation increased exhaled NO•, no ergogenic aids were found on the examined parameters at rest and after resistive breathing to task failure in older adults.


Assuntos
Citrulina , Oxiemoglobinas , Idoso , Humanos , Masculino , Citrulina/farmacologia , Suplementos Nutricionais , Músculos Respiratórios , Estudos Cross-Over
14.
J Funct Morphol Kinesiol ; 8(4)2023 Dec 18.
Artigo em Inglês | MEDLINE | ID: mdl-38132722

RESUMO

The purpose of the present study was to examine the effects of a back squat exercise with unstable load (UN) and traditional free-weight resistance (FWR) on subsequent countermovement jump (CMJ) performance. After familiarisation, thirteen physically active males with experience in resistance training visited the laboratory on two occasions during either experimental (UN) or control (FWR) conditions separated by at least 72 h. In both sessions, participants completed a task-specific warm-up routine followed by three maximum CMJs (pre-intervention; baseline) and a set of three repetitions of either UN or FWR back squat exercise at 85% 1-RM. During the UN condition, the unstable load was suspended from the bar with elastic bands and accounted for 15% of the total load. Post-intervention, three maximum CMJs were performed at 30 s, 4 min, 8 min and 12 min after the last repetition of the intervention. The highest CMJ for each participant was identified for each timepoint. No significant increases (p > 0.05) in jump height, peak concentric power, or peak rate of force development (RFD) were found after the FWR or UN conditions at any timepoint. The lack of improvements following both FWR and UN conditions may be a consequence of the low percentage of unstable load and the inclusion of a comprehensive task-specific warm-up. Further research is required to explore higher UN load percentages (>15%) and the chronic effects following the implementation of a resistance training programme.

15.
J Alzheimers Dis Rep ; 7(1): 1475-1490, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38225966

RESUMO

Background: Virtual reality (VR) technology has become increasingly used for assessment and intervention in the neuroscience field. Objective: We aimed to investigate the effects of a VR Training System, named VRADA (VR Exercise App for Dementia and Alzheimer's Patients), on the cognitive functioning of older people with mild cognitive impairment (MCI). Methods: In this intervention study, 122 older adults with MCI were randomly assigned to five groups (the VRADA group (n = 28), a bike group (n = 11), a physical exercise group (n = 24), a mixed group (physical and cognitive exercise) (n = 31), and a non-contact control group (n = 28). The VRADA group underwent 32 physical and cognitive training sessions, performed 2 or 3 times weekly for 12 weeks in the VR environment. All participants had detailed neuropsychological assessments before and after intervention. Results: A series of linear regression models revealed that the VRADA group showed improvement or no deterioration in cognitive decline in global cognitive function (MMSE), verbal memory (Rey Auditory Verbal Learning Test and WAIS forward test), and executive functions, mental flexibility (Trail Making Test B). Conclusions: This interventionstudy indicates that the VRADA system improves the cognitive function of elders with MCI.

16.
Diagnostics (Basel) ; 12(10)2022 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-36292081

RESUMO

Stroke is an acute neurological dysfunction attributed to a focal injury of the central nervous system due to reduced blood flow to the brain. Nowadays, stroke is a global threat associated with premature death and huge economic consequences. Hence, there is an urgency to model the effect of several risk factors on stroke occurrence, and artificial intelligence (AI) seems to be the appropriate tool. In the present study, we aimed to (i) develop reliable machine learning (ML) prediction models for stroke disease; (ii) cope with a typical severe class imbalance problem, which is posed due to the stroke patients' class being significantly smaller than the healthy class; and (iii) interpret the model output for understanding the decision-making mechanism. The effectiveness of the proposed ML approach was investigated in a comparative analysis with six well-known classifiers with respect to metrics that are related to both generalization capability and prediction accuracy. The best overall false-negative rate was achieved by the Multi-Layer Perceptron (MLP) classifier (18.60%). Shapley Additive Explanations (SHAP) were employed to investigate the impact of the risk factors on the prediction output. The proposed AI method could lead to the creation of advanced and effective risk stratification strategies for each stroke patient, which would allow for timely diagnosis and the right treatments.

17.
Sci Rep ; 12(1): 6647, 2022 04 22.
Artigo em Inglês | MEDLINE | ID: mdl-35459787

RESUMO

Anterior cruciate ligament (ACL) deficient and reconstructed knees display altered biomechanics during gait. Identifying significant gait changes is important for understanding normal and ACL function and is typically performed by statistical approaches. This paper focuses on the development of an explainable machine learning (ML) empowered methodology to: (i) identify important gait kinematic, kinetic parameters and quantify their contribution in the diagnosis of ACL injury and (ii) investigate the differences in sagittal plane kinematics and kinetics of the gait cycle between ACL deficient, ACL reconstructed and healthy individuals. For this aim, an extensive experimental setup was designed in which three-dimensional ground reaction forces and sagittal plane kinematic as well as kinetic parameters were collected from 151 subjects. The effectiveness of the proposed methodology was evaluated using a comparative analysis with eight well-known classifiers. Support Vector Machines were proved to be the best performing model (accuracy of 94.95%) on a group of 21 selected biomechanical parameters. Neural Networks accomplished the second best performance (92.89%). A state-of-the-art explainability analysis based on SHapley Additive exPlanations (SHAP) and conventional statistical analysis were then employed to quantify the contribution of the input biomechanical parameters in the diagnosis of ACL injury. Features, that would have been neglected by the traditional statistical analysis, were identified as contributing parameters having significant impact on the ML model's output for ACL injury during gait.


Assuntos
Lesões do Ligamento Cruzado Anterior , Ligamento Cruzado Anterior , Lesões do Ligamento Cruzado Anterior/diagnóstico , Fenômenos Biomecânicos , Marcha , Humanos , Articulação do Joelho , Aprendizado de Máquina
18.
Artigo em Inglês | MEDLINE | ID: mdl-36612771

RESUMO

Modern lifestyles require new tools for determining a person's ability to return to daily activities after knee surgery. These quantitative instruments must feature high discrimination, be non-invasive, and be inexpensive. Machine learning is a revolutionary approach that has the potential to satisfy the aforementioned requirements and bridge the knowledge gap. The scope of this study is to summarize the results of a systematic literature review on the identification of gait-related changes and the determination of the functional recovery status of patients after knee surgery using advanced machine learning algorithms. The current systematic review was conducted using multiple databases in accordance with the PRISMA guidelines, including Scopus, PubMed, and Semantic Scholar. Six out of the 405 articles met our inclusion criteria and were directly related to the quantification of the recovery status using machine learning and gait data. The results were interpreted using appropriate metrics. The results demonstrated a recent increase in the use of sophisticated machine learning techniques that can provide robust decision-making support during personalized post-treatment interventions for knee-surgery patients.


Assuntos
Marcha , Articulação do Joelho , Humanos , Joelho/cirurgia , Aprendizado de Máquina , Algoritmos
19.
Arthroscopy ; 27(12): 1654-62, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-21937193

RESUMO

PURPOSE: To evaluate in vivo the differences in tibial rotation between single- and double-bundle anterior cruciate ligament (ACL)-reconstructed knees under combined loading conditions. METHODS: An 8-camera optoelectronic system and a force plate were used to collect kinematic and kinetic data from 14 patients with double-bundle ACL reconstruction, 14 patients with single-bundle reconstruction, 12 ACL-deficient subjects, and 12 healthy control individuals while performing 2 tasks. The first included walking, 60° pivoting, and stair ascending, and the second included stair descending, 60° pivoting, and walking. The 2 variables evaluated were the maximum range of internal-external tibial rotation and the maximum knee rotational moment. RESULTS: Tibial rotation angles were not significantly different across the 4 groups (P = .331 and P = .851, respectively) or when side-to-side differences were compared within groups (P = .216 and P = .371, respectively) for the ascending and descending maneuvers, nor were rotational moments among the 4 groups (P = .418 and P = .290, respectively). Similarly, for the descending maneuver, the rotational moments were not significantly different between sides (P = .192). However, for the ascending maneuver, rotational moments of the affected sides were significantly lower by 20.5% and 18.7% compared with their intact counterparts in the single-bundle (P = .015) and double-bundle (P = .05) groups, respectively. CONCLUSIONS: High-intensity activities combining stair ascending or descending with pivoting produce similar tibial rotation in single- and double-bundle ACL-reconstructed patients. During such maneuvers, the reconstructed knee may be subjected to significantly lower rotational loads compared with the intact knee. LEVEL OF EVIDENCE: Level III, retrospective comparative study.


Assuntos
Reconstrução do Ligamento Cruzado Anterior/métodos , Ligamento Cruzado Anterior/cirurgia , Traumatismos do Joelho/cirurgia , Técnicas de Sutura/instrumentação , Suturas , Tíbia/cirurgia , Adulto , Lesões do Ligamento Cruzado Anterior , Fenômenos Biomecânicos , Desenho de Equipamento , Seguimentos , Humanos , Masculino , Estudos Retrospectivos , Rotação , Ruptura , Resultado do Tratamento , Gravação em Vídeo/instrumentação
20.
Physiol Rep ; 9(1): e14656, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33400851

RESUMO

We examined changes in selected muscle performance parameters after 8 weeks of interval training using two opposite running inclinations. We hypothesized that the uphill training will affect endurance muscle performance outcomes, whereas the downhill training will affect power muscle performance outcomes. Fourteen physically active volunteers were randomly assigned into either the Uphill group (UG; n = 7; uphill interval running at +10% incline) or the Downhill group (DG; n = 7; downhill interval running at -10% incline) and completed 16 training sessions. Each session consisted of ten 30 s treadmill runs at 90% of maximum aerobic speed (MAS) with a work to rest ratio of 1:2. Vertical jump performance, isometric (MVC) and isokinetic torque of knee extensors and flexors, and fatigue of knee extensors were evaluated pre and post-training. Moreover, body composition (via bioimpedance) and vastus lateralis muscle architecture (via ultrasonography) were assessed pre and post-training. Relative lean tissue mass, relative fat mass, and squat jump (cm) significantly (p < .05) changed from baseline values by +4.5 ± 4.0%, -11.5 ± 9.6%, and +9.5 ± 11.7%, respectively, only in the DG. Similarly, DG improved absolute values of knee extension rate of torque development and impulse (p < .05), whereas knee flexion peak torque angle significantly decreased in both groups (p < .05). On the other hand, the UG increased the number of repetitions achieved during the fatigue protocol and total work by 21.2 ± 32.6% and 13.8 ± 21.2%, respectively (p < .05). No differences were found between groups in muscle architecture. Introducing variations in slope during HIIT could be used to induce specific improvements toward muscle endurance or power performance characteristics.


Assuntos
Força Muscular/fisiologia , Músculo Esquelético/fisiologia , Músculo Quadríceps/fisiologia , Corrida , Adulto , Teste de Esforço/métodos , Feminino , Humanos , Masculino , Contração Muscular , Torque , Adulto Jovem
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