Detalhe da pesquisa
1.
Identification and analysis of individuals who deviate from their genetically-predicted phenotype.
PLoS Genet
; 19(9): e1010934, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37733769
2.
Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk.
Hum Mol Genet
; 32(3): 496-505, 2023 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36048866
3.
Reduced penetrance of MODY-associated HNF1A/HNF4A variants but not GCK variants in clinically unselected cohorts.
Am J Hum Genet
; 109(11): 2018-2028, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36257325
4.
Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies.
Am J Hum Genet
; 109(9): 1638-1652, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055212
5.
Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight.
Hum Mol Genet
; 31(11): 1762-1775, 2022 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34897462
6.
Integrating multiple lines of evidence to assess the effects of maternal BMI on pregnancy and perinatal outcomes.
BMC Med
; 22(1): 32, 2024 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38281920
7.
A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor.
PLoS Genet
; 17(6): e1009577, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34111113
8.
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.
PLoS Genet
; 17(4): e1009525, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33886544
9.
Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood.
Diabetologia
; 66(8): 1472-1480, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37280435
10.
Large Copy-Number Variants in UK Biobank Caused by Clonal Hematopoiesis May Confound Penetrance Estimates.
Am J Hum Genet
; 107(2): 325-329, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32574563
11.
Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study.
BMC Med
; 21(1): 355, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37710313
12.
Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study.
BMC Med
; 21(1): 501, 2023 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110912
13.
Mendelian randomisation study of body composition and depression in people of East Asian ancestry highlights potential setting-specific causality.
BMC Med
; 21(1): 37, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36726144
14.
Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study.
Eur J Epidemiol
; 38(7): 795-807, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37133737
15.
Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review.
Eur J Epidemiol
; 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938447
16.
Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank.
Br J Cancer
; 127(8): 1534-1539, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35978138
17.
Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.
Am J Hum Genet
; 104(2): 275-286, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30665703
18.
GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology.
Am J Hum Genet
; 104(1): 157-163, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30583798
19.
Investigating the effect of sexual behaviour on oropharyngeal cancer risk: a methodological assessment of Mendelian randomization.
BMC Med
; 20(1): 40, 2022 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35094705
20.
Detection and characterization of male sex chromosome abnormalities in the UK Biobank study.
Genet Med
; 24(9): 1909-1919, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35687092