Detalhe da pesquisa
1.
A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling.
Cell
; 165(3): 643-55, 2016 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27104980
2.
Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα.
Proc Natl Acad Sci U S A
; 119(38): e2210769119, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36095215
3.
Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay.
Bioorg Med Chem
; 42: 116246, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34130216
4.
Synthetic molecules for disruption of the MYC protein-protein interface.
Bioorg Med Chem
; 26(14): 4234-4239, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30037753
5.
The butterfly effect in cancer: a single base mutation can remodel the cell.
Proc Natl Acad Sci U S A
; 112(4): 1131-6, 2015 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25583473
6.
Oncogenic activity of the regulatory subunit p85ß of phosphatidylinositol 3-kinase (PI3K).
Proc Natl Acad Sci U S A
; 111(47): 16826-9, 2014 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25385636
7.
Inhibitor of MYC identified in a Kröhnke pyridine library.
Proc Natl Acad Sci U S A
; 111(34): 12556-61, 2014 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25114221
8.
Phosphatidylinositol 4,5-bisphosphate-specific AKT1 is oncogenic.
Int J Cancer
; 127(1): 239-44, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19876913
9.
Akt-mediated regulation of NFkappaB and the essentialness of NFkappaB for the oncogenicity of PI3K and Akt.
Int J Cancer
; 125(12): 2863-70, 2009 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19609947
10.
Synthesis and evaluation of a cyclic imine derivative conjugated to a fluorescent molecule for labeling of proteins.
Bioorg Med Chem Lett
; 19(4): 1210-3, 2009 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19136260
11.
MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.
Cancer Cell
; 25(4): 469-83, 2014 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24735923
12.
Protein expression profiles of C3H 10T1/2 murine fibroblasts and of isogenic cells transformed by the H1047R mutant of phosphoinositide 3-kinase (PI3K).
Cell Cycle
; 10(6): 971-6, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21350335