Manifestations and management of osteochondromas: a retrospective analysis of 382 patients.

Osteochondromas represent the most common primary bone tumours; they reportedly represent 20-50% of all benign bone tumours and 10-15% of all bone tumours. Malignant transformation is their most severe complication. However, deformities and interference with major joint function are the most frequent complaints in patients with hereditary multiple osteochondroma. Treatment should therefore aim not only at surgical resection of the masses but also at prevention of deformities. This article reports observations made on 69 patients with hereditary multiple osteochondroma and 313 patients with solitary osteochondroma, with a mean follow-up of 13.4 years.

[Selection of treatment modalities in children with chronic osteomyelitis]. / Kronik osteomiyelitli çocuklarda cerrahi tedavi yöntemlerinin seçimi.

OBJECTIVES: We evaluated clinical and follow-up findings and treatment methods of pediatric patients with chronic osteomyelitis. METHODS: The study included 22 children (14 boys, 8 girls; mean age 8+/-7 years) who were treated for chronic osteomyelitis. Infection sites were the femur, tibia, ulna, and radius in 11, 8, 1, and 2 patients, respectively. Sixteen patients had a history of trauma. Fourteen patients had fractures, nine of which were associated with segmentary bone defects. All the patients underwent at least one debridement and received antibiotic treatment for at least six weeks. When necessary, medications were modified according to the antibiogram results. Cast immobilization was applied, but external fixation was used when bone instability existed. The mean follow-up period was 54 months. RESULTS: Clinical improvement was achieved in 13 patients following surgical debridement procedures, antibiotic treatment for six weeks, secondary grafting (5 patients), and cast immobilization. Of nine patients with segmentary bone losses, seven patients needed bone reconstruction procedures. Spontaneous shaft regeneration was observed in one patient with ulnar osteomyelitis. CONCLUSION: The results of surgical debridement and antibiotic treatment are satisfactory in more than half of the pediatric patients with chronic osteomyelitis. However, those developing segmentary bone defects after surgical debridement require bone reconstruction procedures.

Lengthening procedures of small bones of foot and foot stump.

Foot length discrepancy may result from congenital or acquired causes. If the absence of the foot is more proximal than the metatarsal level, push off and foot resilience will be disturbed and rapid walking and spring will be awkward. Those patients have to be fitted with a prosthesis extending above the ankle to the distal leg. The functional impairment and poor cosmetic appearance become social problems especially for adolescents. Twelve cases underwent a lengthening procedure of small bones of the foot in our clinic since 1995 to lengthen the foot or a foot stump. Results were satisfactory.

Carpal tunnel release: using a short vertical incision above the flexor crease of the wrist.

BACKGROUND: Numerous surgical incision techniques have been used to treat carpal tunnel syndrome. The advantages and disadvantages of each are a matter of debate. However, the technique should be cost effective and also decrease the amount of time needed before the patient can return to work. A minimally invasive surgical procedure for the treatment of carpal tunnel syndrome is described in this report. METHODS: Ninety-six patients with carpal tunnel syndrome (106 wrists) were operated on through a 2 cm vertical incision, above the flexor crease of the wrist, under local infiltration anesthesia, without tourniquet control. The mean time length of the operation was nine minutes. RESULTS: Numbness and night pain disappeared in all cases postoperatively. The mean time period to return to work and full activity was 18 (12-26) days. CONCLUSION: Decreasing the time needed before the patient can return to work, minimizing the rate of complications and reducing hospital costs are advantages of this technique.

Conservative treatment in intra-articular fractures of the distal radius: a study on the functional and anatomic outcome in elderly patients.

Fractures of the distal radius are common among elderly patients. Although the indications for surgical treatment are clearly defined, there are patients who will not consent to an operation, even when it is indicated. Inevitably, these cases will require conservative treatment. The aim of this study was to determine the relation between the functional and anatomic stati of these patients. One hundred and eight patients, with intra-articular distal radial fractures, who had been treated non-surgically, were investigated in this study. Functional and anatomic assessments were also performed. The mean follow up period was 39.5 months. The mean age of the subjects was 73.9 years. Although 25.9% of the patients had fair and poor anatomic scores, 88.9% were considered to have good and excellent functional results.

Avoiding iatrogenic radial nerve injury during humeral fracture surgery: a modified approach to the distal humerus.

OBJECTIVE: Our aim was to assess the results of posterior retraction technique to prevent iatrogenic radial nerve injury during humeral fracture surgery. METHODS: Seventy-two patients who underwent surgery for a distal humerus fracture between 1996 and 2002 were reviewed. These 72 patients comprised Group 1. Following a cadaveric study on the vascularization of the radial nerve, a modified surgical approach was undertaken starting in 2002. Sixty-one patients who underwent this new surgical approach were included in Group 2. The rates of radial nerve deficit of the groups were compared using the Pearson chi-square test. RESULTS: In Group 1, 19 iatrogenic nerve deficits occurred. After defining the blood circulation of the nerve, the lateral approach was modified. The anterolateral side of the nerve was released and the nerve was left attached to the triceps muscle. In Group 2, one patient developed postoperative transient nerve deficit. CONCLUSION: The radial nerve is supplied by the branches of the deep brachial artery in close relation with the triceps muscle. Anterior dissection and posterior retraction of the radial nerve during lateral approach may preserve its blood supply and reduces the risk of iatrogenic injury.

Gait symmetry in patients with unilateral partial hip arthroplasty.

OBJECTIVES: In this study gait deviations symmetry and asymmetry in patients with unilateral partial hip arthroplasty was determined. PATIENTS AND METHODS: Gait characteristics and time since operation (11.9+/-6.1; range 7 to 29 months) of 16 patients (9 females, 7 males; mean age 61.5+/-16.5 years; range 27 to 86 years) with unilateral partial hip arthroplasty were evaluated. Ten healthy volunteers (3 females, 7 males; mean age 54.1+/-11.9 years; range 35 to 65 years) were included in the study as control group. Quantitative gait data was collected with the Vicon 370 System (Oxford Metrics, Oxford, UK). Spatio-temporal (walking velocity, cadence, step time, step length, double support time) and kinematic (joint rotation angles of pelvis and hip in sagittal plane) data were processed by using Vicon Clinical Manager software package. Spatio-temporal and kinematic gait symmetry indices of both groups were calculated. RESULTS: Spatio-temporal and kinematic gait characteristics, but not the symmetry indices, of patients with unilateral partial hip arthroplasty were different from the control group (p>0.05). CONCLUSION: Findings of this study reveal that patients with unilateral partial hip arthroplasty had various gait deviations compared to healthy subjects, but that symmetry was preserved.

Timing of surgical treatment for type III supracondylar humerus fractures in pediatric patients.

BACKGROUND: Type III supracondylar humeral fracture is a common cause of emergency hospitalization among children requiring surgical treatment. The configuration of the internal fixation material, surgical technique, and optimal timing of surgery (TS) have always been popular topics of debate. The TS in uncomplicated cases is usually determined by surgeons. METHODS: In this study, we prospectively followed children with type III supracondylar fractures. We aimed to clarify the effects of injury side, gender, and post-injury delay on switching to open surgery and the ease of the reduction. RESULTS: Based on our results, the probability of switching to open surgery increased by a factor of 4 every 5 h beginning 15 h after injury. Open surgery was necessary after 32 h. CONCLUSION: Reduction became technically more difficult as TS increased.

The effect of prophylactic dose of a low molecular weight heparin on skin wound healing of rats.

PURPOSE: To investigate the effect of prophylactic dose of a low molecular weight heparin, enoxaparin, on skin wound healing of rats. METHODS: Forty rats were used for the study. Rats were randomly assigned to two equal groups. Experimental group received prophylactic dose of enoxaparin. Physiologic saline was administered to the control group. Parameters of wound healing of experimental and control groups were compared. For comparison of the groups in terms of fibrosis, vascularization, inflammation, epithelization, and tensile strength test (Newton). Mann-Whitney-U test was used because variables were categorical data (fibrosis, vascularization, inflammation and epithelization). Differences between groups were analyzed with independent samples t-test (tensile strength). Significance was set at p<0.05. RESULTS: Skin wound of the experimental group presented tensile strength significantly decreased (p<0.001), histopathologic examination revealed a significant (p<0.001) delayed epithelization and decreased in fibrosis, vascularization, inflammation (p<0.001) in the experimental group. CONCLUSION: Enoxaparin delay wound healing by decreased inflammatory cells, fibroblast contents and their products (growth factors), and by promoted hemorrhage.

Blood loss evaluation in children under the age of 11 with femoral shaft fractures patients with isolated versus multiple injuries.

BACKGROUND: Blood loss from non-cavitary hemorrhages is a significant source of hypovolemic shock in trauma patients. It has been reported that pediatric femoral fractures do not cause excess blood loss if there is no additional injury or trauma. The purpose of this study was to define the magnitude of blood loss resulting from pediatric femoral fractures and the factors influencing the loss. METHODS: Twenty children under the age of 11 with femoral shaft fractures were included in this study. The patients' data were collected prospectively for 2 years. Hemoglobin concentrations, hematocrit levels, emergency room records, and clinical findings were evaluated and additional injuries were considered. RESULTS AND CONCLUSION: The patients with additional trauma showed significant decreases in both hemoglobin concentrations and hematocrit levels, comparison with the patients who had only isolated femoral fractures. If there is an obvious decrease in hematocrit and/or hemoglobin concentration in a child with a femoral fracture, the possibility of additional injuries should be investigated.

The effect of prophylactic dose of a low molecular weight heparin on skin wound healing of rats / Efeito da dose profilática de heparina de baixo peso molecular na cicatrização de feridas na pele de ratos

PURPOSE: To investigate the effect of prophylactic dose of a low molecular weight heparin, enoxaparin, on skin wound healing of rats. METHODS: Forty rats were used for the study. Rats were randomly assigned to two equal groups. Experimental group received prophylactic dose of enoxaparin. Physiologic saline was administered to the control group. Parameters of wound healing of experimental and control groups were compared. For comparison of the groups in terms of fibrosis, vascularization, inflammation, epithelization, and tensile strength test (Newton). Mann-Whitney-U test was used because variables were categorical data (fibrosis, vascularization, inflammation and epithelization). Differences between groups were analyzed with independent samples t-test (tensile strength). Significance was set at p<0.05. RESULTS: Skin wound of the experimental group presented tensile strength significantly decreased (p<0.001), histopathologic examination revealed a significant (p<0.001) delayed epithelization and decreased in fibrosis, vascularization, inflammation (p<0.001) in the experimental group. CONCLUSION: Enoxaparin delay wound healing by decreased inflammatory cells, fibroblast contents and their products (growth factors), and by promoted hemorrhage.

OBJETIVO: Investigar o efeito de dose profilática da heparina de baixo peso molecular, enoxaparina, na cicatrização de feridas na pele de ratos. MÉTODOS: Quarenta ratos foram utilizados para o estudo. Ratos foram distribuídos aleatoriamente a dois grupos iguais. O grupo experimental recebeu profilática de enoxaparina. Solução salina fisiologica foi administrada ao grupo controle. Foram comparados parâmetros de cicatrização dos grupos experimental e controle.Os grupos foram comparados em termos de fibrose, vascularização, inflamação, epitelização e força tensil (teste de Newton). Foi realizado o teste de Mann-Whitney-U para variáveis com dados categóricos (fibrose, cicatrização, inflamação e epitelização). Diferenças entre os grupos foram analisadas como amostras independentes pelo t-teste (força tensil). Significância foi fixada para p < 0,05. RESULTADOS: A ferida do grupo experimental apresentou força tensil diminuída significativamente (p < 0,001), o exame histopatológico revelou um significativo (p < 0,001) retardo na epitelização e diminuição na fibrose, cicatrização, inflamação (p < 0,001) no grupo experimental. CONCLUSÃO: A enoxaparina retarda a cicatrização da ferida pela diminuição das células inflamatórias, pelo menor conteúdo de fibroblasto e seus produtos (fatores de crescimento) e por promover hemorragia. O grupo experimental foi incluído pela perda significativa da força tênsil no presente estudo.