Pesquisa | BVS IEC

1.

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing.

Lo Sardo, Valentina; Chubukov, Pavel; Ferguson, William; Kumar, Aditya; Teng, Evan L; Duran, Michael; Zhang, Lei; Cost, Gregory; Engler, Adam J; Urnov, Fyodor; Topol, Eric J; Torkamani, Ali; Baldwin, Kristin K.

Cell ; 175(7): 1796-1810.e20, 2018 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-30528432

2.

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.

Soldner, Frank; Laganière, Josée; Cheng, Albert W; Hockemeyer, Dirk; Gao, Qing; Alagappan, Raaji; Khurana, Vikram; Golbe, Lawrence I; Myers, Richard H; Lindquist, Susan; Zhang, Lei; Guschin, Dmitry; Fong, Lauren K; Vu, B Joseph; Meng, Xiangdong; Urnov, Fyodor D; Rebar, Edward J; Gregory, Philip D; Zhang, H Steve; Jaenisch, Rudolf.

Cell ; 146(2): 318-31, 2011 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-21757228

3.

Distinct factors control histone variant H3.3 localization at specific genomic regions.

Goldberg, Aaron D; Banaszynski, Laura A; Noh, Kyung-Min; Lewis, Peter W; Elsaesser, Simon J; Stadler, Sonja; Dewell, Scott; Law, Martin; Guo, Xingyi; Li, Xuan; Wen, Duancheng; Chapgier, Ariane; DeKelver, Russell C; Miller, Jeffrey C; Lee, Ya-Li; Boydston, Elizabeth A; Holmes, Michael C; Gregory, Philip D; Greally, John M; Rafii, Shahin; Yang, Chingwen; Scambler, Peter J; Garrick, David; Gibbons, Richard J; Higgs, Douglas R; Cristea, Ileana M; Urnov, Fyodor D; Zheng, Deyou; Allis, C David.

Cell ; 140(5): 678-91, 2010 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-20211137

4.

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.

Sexton, Alec N; Regalado, Samuel G; Lai, Christine S; Cost, Gregory J; O'Neil, Colleen M; Urnov, Fyodor D; Gregory, Philip D; Jaenisch, Rudolf; Collins, Kathleen; Hockemeyer, Dirk.

Genes Dev ; 28(17): 1885-99, 2014 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-25128433

5.

Hijack of CRISPR defences by selfish genes holds clinical promise.

Urnov, Fyodor D.

Nature ; 571(7764): 180-181, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31285598

6.

An ode to gene edits that prevent deafness.

Urnov, Fyodor.

Nature ; 553(7687): 162-163, 2018 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-32086502

7.

An ode to gene edits that prevent deafness.

Urnov, Fyodor.

Nature ; 553(7687): 162-163, 2018 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-29323325

8.

Translating dosage compensation to trisomy 21.

Jiang, Jun; Jing, Yuanchun; Cost, Gregory J; Chiang, Jen-Chieh; Kolpa, Heather J; Cotton, Allison M; Carone, Dawn M; Carone, Benjamin R; Shivak, David A; Guschin, Dmitry Y; Pearl, Jocelynn R; Rebar, Edward J; Byron, Meg; Gregory, Philip D; Brown, Carolyn J; Urnov, Fyodor D; Hall, Lisa L; Lawrence, Jeanne B.

Nature ; 500(7462): 296-300, 2013 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-23863942

9.

Prime Time for Genome Editing?

Urnov, Fyodor D.

N Engl J Med ; 382(5): 481-484, 2020 01 30.

Artigo em Inglês | MEDLINE | ID: mdl-31995698

10.

Improved specificity of TALE-based genome editing using an expanded RVD repertoire.

Miller, Jeffrey C; Zhang, Lei; Xia, Danny F; Campo, John J; Ankoudinova, Irina V; Guschin, Dmitry Y; Babiarz, Joshua E; Meng, Xiangdong; Hinkley, Sarah J; Lam, Stephen C; Paschon, David E; Vincent, Anna I; Dulay, Gladys P; Barlow, Kyle A; Shivak, David A; Leung, Elo; Kim, Jinwon D; Amora, Rainier; Urnov, Fyodor D; Gregory, Philip D; Rebar, Edward J.

Nat Methods ; 12(5): 465-71, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25799440

11.

Functional footprinting of regulatory DNA.

Vierstra, Jeff; Reik, Andreas; Chang, Kai-Hsin; Stehling-Sun, Sandra; Zhou, Yuanyue; Hinkley, Sarah J; Paschon, David E; Zhang, Lei; Psatha, Nikoletta; Bendana, Yuri R; O'Neil, Colleen M; Song, Alexander H; Mich, Andrea K; Liu, Pei-Qi; Lee, Gary; Bauer, Daniel E; Holmes, Michael C; Orkin, Stuart H; Papayannopoulou, Thalia; Stamatoyannopoulos, George; Rebar, Edward J; Gregory, Philip D; Urnov, Fyodor D; Stamatoyannopoulos, John A.

Nat Methods ; 12(10): 927-30, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-26322838

12.

Genome editing: The domestication of Cas9.

Urnov, Fyodor.

Nature ; 529(7587): 468-9, 2016 Jan 28.

Artigo em Inglês | MEDLINE | ID: mdl-26819037

13.

Imagine CRISPR cures.

Urnov, Fyodor D.

Mol Ther ; 29(11): 3103-3106, 2021 11 03.

Artigo em Inglês | MEDLINE | ID: mdl-34710352

14.

Genome editing with engineered zinc finger nucleases.

Urnov, Fyodor D; Rebar, Edward J; Holmes, Michael C; Zhang, H Steve; Gregory, Philip D.

Nat Rev Genet ; 11(9): 636-46, 2010 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-20717154

15.

Don't edit the human germ line.

Lanphier, Edward; Urnov, Fyodor; Haecker, Sarah Ehlen; Werner, Michael; Smolenski, Joanna.

Nature ; 519(7544): 410-1, 2015 Mar 26.

Artigo em Inglês | MEDLINE | ID: mdl-25810189

16.

Call for Papers: Expanding the Scale and Scope of Therapeutic Gene Editing.

Kiem, Hans-Peter; Gaudelli, Nicole N; Urnov, Fyodor D; Frederickson, Robert M; Herzog, Roland W.

Mol Ther ; 28(8): 1743, 2020 08 05.

Artigo em Inglês | MEDLINE | ID: mdl-32679031

17.

Cas9 in action: no more known unknowns?

Urnov, Fyodor D.

Nat Methods ; 14(6): 563-564, 2017 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-28557979

18.

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.

Straimer, Judith; Lee, Marcus C S; Lee, Andrew H; Zeitler, Bryan; Williams, April E; Pearl, Jocelynn R; Zhang, Lei; Rebar, Edward J; Gregory, Philip D; Llinás, Manuel; Urnov, Fyodor D; Fidock, David A.

Nat Methods ; 9(10): 993-8, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22922501

19.

Biological techniques: Edit the genome to understand it.

Urnov, Fyodor D.

Nature ; 513(7516): 40-1, 2014 Sep 04.

Artigo em Inglês | MEDLINE | ID: mdl-25141180

20.

Precise genome modification in the crop species Zea mays using zinc-finger nucleases.

Shukla, Vipula K; Doyon, Yannick; Miller, Jeffrey C; DeKelver, Russell C; Moehle, Erica A; Worden, Sarah E; Mitchell, Jon C; Arnold, Nicole L; Gopalan, Sunita; Meng, Xiangdong; Choi, Vivian M; Rock, Jeremy M; Wu, Ying-Ying; Katibah, George E; Zhifang, Gao; McCaskill, David; Simpson, Matthew A; Blakeslee, Beth; Greenwalt, Scott A; Butler, Holly J; Hinkley, Sarah J; Zhang, Lei; Rebar, Edward J; Gregory, Philip D; Urnov, Fyodor D.

Nature ; 459(7245): 437-41, 2009 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-19404259

BVS IEC

Instituto Evandro Chagas

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar:

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing.

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.

Distinct factors control histone variant H3.3 localization at specific genomic regions.

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.

Hijack of CRISPR defences by selfish genes holds clinical promise.

An ode to gene edits that prevent deafness.

An ode to gene edits that prevent deafness.

Translating dosage compensation to trisomy 21.

Prime Time for Genome Editing?

Improved specificity of TALE-based genome editing using an expanded RVD repertoire.

Functional footprinting of regulatory DNA.

Genome editing: The domestication of Cas9.

Imagine CRISPR cures.

Genome editing with engineered zinc finger nucleases.

Don't edit the human germ line.

Call for Papers: Expanding the Scale and Scope of Therapeutic Gene Editing.

Cas9 in action: no more known unknowns?

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.

Biological techniques: Edit the genome to understand it.

Precise genome modification in the crop species Zea mays using zinc-finger nucleases.