Detalhe da pesquisa
1.
Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice.
Br J Anaesth
; 125(3): 298-307, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32624183
2.
Hypothalamic inflammation in the control of metabolic function.
Annu Rev Physiol
; 77: 131-60, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25668019
3.
Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity.
Biochim Biophys Acta
; 1861(9 Pt A): 1083-1095, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27317983
4.
Lipin-1 integrates lipid synthesis with proinflammatory responses during TLR activation in macrophages.
J Immunol
; 193(9): 4614-22, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25252959
5.
Identification of AgRP cells in the murine hindbrain that drive feeding.
Mol Metab
; 80: 101886, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38246589
6.
Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages.
J Biol Chem
; 287(14): 10894-904, 2012 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22334674
7.
Subcellular localization and role of lipin-1 in human macrophages.
J Immunol
; 186(10): 6004-13, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21478406
8.
Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance.
Cell Metab
; 35(9): 1613-1629.e8, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37572666
9.
Metabolic factors in the regulation of hypothalamic innate immune responses in obesity.
Exp Mol Med
; 54(4): 393-402, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35474339
10.
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis.
Sci Signal
; 15(733): eabj8204, 2022 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35536884
11.
Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages.
J Immunol
; 183(4): 2767-74, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19625654
12.
Microglial Lipid Biology in the Hypothalamic Regulation of Metabolic Homeostasis.
Front Endocrinol (Lausanne)
; 12: 668396, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34122343
13.
The cationic cluster of group IVA phospholipase A2 (Lys488/Lys541/Lys543/Lys544) is involved in translocation of the enzyme to phagosomes in human macrophages.
J Lipid Res
; 51(2): 388-99, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19717620
14.
Hypothalamic microglia as potential regulators of metabolic physiology.
Nat Metab
; 1(3): 314-320, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32694719
15.
mTORC1 to AMPK switching underlies ß-cell metabolic plasticity during maturation and diabetes.
J Clin Invest
; 129(10): 4124-4137, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31265435
16.
Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice.
JCI Insight
; 2(7): e91229, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28405620
17.
Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier.
Cell Rep
; 19(11): 2257-2271, 2017 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28614713
18.
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility.
Cell Metab
; 26(1): 185-197.e3, 2017 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28683286
19.
Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells.
Cell Rep
; 14(11): 2611-23, 2016 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26971994
20.
Leptin potentiates astrogenesis in the developing hypothalamus.
Mol Metab
; 4(11): 881-9, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26629411