Detalhe da pesquisa
1.
Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum.
PLoS Pathog
; 6(5): e1000887, 2010 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20485514
2.
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum.
Bioorg Med Chem
; 17(4): 1527-33, 2009 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19195901
3.
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
Cell Host Microbe
; 4(6): 567-78, 2008 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19064257
4.
X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy.
J Biol Chem
; 282(35): 25436-44, 2007 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-17567585
5.
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
J Infect Dis
; 194(4): 528-35, 2006 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16845638
6.
Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2'-substituted triclosan derivatives.
Bioorg Med Chem Lett
; 16(8): 2163-9, 2006 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16466916
7.
Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.
Bioorg Med Chem Lett
; 15(23): 5247-52, 2005 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16198563