Detalhe da pesquisa
1.
An altered expression of miR-376a-3p and miR-20a-5p in peripheral blood exosomes regulates the autophagy and inflammatory systemic substrates, and relates to the smoking habit and age in Crohn's disease.
FASEB J
; 38(2): e23418, 2024 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38226870
2.
A positive feedback loop between AMPK and GDF15 promotes metformin antidiabetic effects.
Pharmacol Res
; 187: 106578, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36435271
3.
Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC-induced cholestatic injury by promoting a pro-restorative inflammatory response.
J Pathol
; 258(3): 312-324, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36148647
4.
The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice.
Diabetologia
; 65(3): 490-505, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34932133
5.
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach.
Pharmacol Rev
; 70(2): 348-383, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29507103
6.
Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded Protein Response in Human Hepatic Cells.
J Pharmacol Exp Ther
; 374(3): 452-461, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554435
7.
Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation.
J Lipid Res
; 59(12): 2308-2320, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30352954
8.
A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice.
Hepatology
; 65(3): 950-968, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27880981
9.
Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.
Biochim Biophys Acta
; 1861(12 Pt A): 1929-1941, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27686967
10.
Cyclooxygenase-2 expression in hepatocytes attenuates non-alcoholic steatohepatitis and liver fibrosis in mice.
Biochim Biophys Acta
; 1862(9): 1710-23, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27321932
11.
Inhibition of T-cell activation by the CTLA4-Fc Abatacept is sufficient to ameliorate proteinuric kidney disease.
Am J Physiol Renal Physiol
; 312(4): F748-F759, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27440778
12.
Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis.
Hepatology
; 63(2): 604-19, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26313466
13.
Somatostatin protects human retinal pericytes from inflammation mediated by microglia.
Exp Eye Res
; 164: 46-54, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28734673
14.
Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activation.
J Biol Chem
; 290(18): 11663-77, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25792746
15.
IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes.
Biochim Biophys Acta
; 1853(12): 3224-34, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26384875
16.
Somatostatin protects photoreceptor cells against high glucose-induced apoptosis.
Mol Vis
; 22: 1522-1531, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28050125
17.
Friedelane-type triterpenoids as selective anti-inflammatory agents by regulation of differential signaling pathways in LPS-stimulated macrophages.
Toxicol Appl Pharmacol
; 313: 57-67, 2016 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27751938
18.
Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes.
J Biol Chem
; 289(42): 29406-19, 2014 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25204659
19.
Sterile inflammation in acetaminophen-induced liver injury is mediated by Cot/tpl2.
J Biol Chem
; 288(21): 15342-51, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23572518
20.
GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-ß1/SMAD3 pathway.
Metabolism
; 152: 155772, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38176644