Detalhe da pesquisa
1.
Is CAA a perivascular brain clearance disease? A discussion of the evidence to date and outlook for future studies.
Cell Mol Life Sci
; 81(1): 239, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38801464
2.
An electrostatic cluster guides Aß40 fibril formation in sporadic and Dutch-type cerebral amyloid angiopathy.
J Struct Biol
; 216(2): 108092, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38615725
3.
Emergent White Matter Degeneration in the rTg-DI Rat Model of Cerebral Amyloid Angiopathy Exhibits Unique Proteomic Changes.
Am J Pathol
; 192(3): 426-440, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34896071
4.
Insights into Cerebral Amyloid Angiopathy Type 1 and Type 2 from Comparisons of the Fibrillar Assembly and Stability of the Aß40-Iowa and Aß40-Dutch Peptides.
Biochemistry
; 61(12): 1181-1198, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35666749
5.
Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aß40 fibrils.
J Biol Chem
; 297(5): 101259, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34599967
6.
Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy.
Neuropathol Appl Neurobiol
; 48(5): e12804, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35266166
7.
Normal cerebrospinal fluid concentrations of PDGFRß in patients with cerebral amyloid angiopathy and Alzheimer's disease.
Alzheimers Dement
; 18(10): 1788-1796, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34874603
8.
Copper stabilizes antiparallel ß-sheet fibrils of the amyloid ß40 (Aß40)-Iowa variant.
J Biol Chem
; 295(27): 8914-8927, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32376688
9.
Distinct brain regional proteome changes in the rTg-DI rat model of cerebral amyloid angiopathy.
J Neurochem
; 159(2): 273-291, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34218440
10.
Anti-Parallel ß-Hairpin Structure in Soluble Aß Oligomers of Aß40-Dutch and Aß40-Iowa.
Int J Mol Sci
; 22(3)2021 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513738
11.
Robust neuroinflammation and perivascular pathology in rTg-DI rats, a novel model of microvascular cerebral amyloid angiopathy.
J Neuroinflammation
; 17(1): 78, 2020 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32127016
12.
The coarse-grained plaque: a divergent Aß plaque-type in early-onset Alzheimer's disease.
Acta Neuropathol
; 140(6): 811-830, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32926214
13.
Longitudinal Cognitive Decline in a Novel Rodent Model of Cerebral Amyloid Angiopathy Type-1.
Int J Mol Sci
; 21(7)2020 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32231123
14.
Environmental Enrichment: Disentangling the Influence of Novelty, Social, and Physical Activity on Cerebral Amyloid Angiopathy in a Transgenic Mouse Model.
Int J Mol Sci
; 21(3)2020 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32012921
15.
Long-term voluntary wheel running does not alter vascular amyloid burden but reduces neuroinflammation in the Tg-SwDI mouse model of cerebral amyloid angiopathy.
J Neuroinflammation
; 16(1): 144, 2019 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296239
16.
A Novel Transgenic Rat Model of Robust Cerebral Microvascular Amyloid with Prominent Vasculopathy.
Am J Pathol
; 188(12): 2877-2889, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446159
17.
The influence of the amyloid ß-protein and its precursor in modulating cerebral hemostasis.
Biochim Biophys Acta
; 1862(5): 1018-26, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26519139
18.
Animal models of cerebral amyloid angiopathy.
Clin Sci (Lond)
; 131(19): 2469-2488, 2017 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28963121
19.
Mechanism of Nucleated Conformational Conversion of Aß42.
Biochemistry
; 54(27): 4197-207, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26069943
20.
Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice.
J Biol Chem
; 289(25): 17895-908, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24828504