Detalhe da pesquisa
1.
A truncated HIV Tat demonstrates potent and specific latency reversal activity.
Antimicrob Agents Chemother
; 67(11): e0041723, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37874295
2.
Differential gene expression, irrespective of circulating Hepatitis B Surface Antigen levels, between Inactive Carrier and Nucleos(t)ide Analogue-Treated Hepatitis B Virus patients.
J Infect Dis
; 225(8): 1471-1476, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33009569
3.
In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System.
Int J Mol Sci
; 17(4): 584, 2016 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27092500
4.
Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy.
Chem Res Toxicol
; 28(10): 1914-25, 2015 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26313431
5.
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.
Mol Neurodegener
; 19(1): 37, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38654375
6.
Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?
Eur J Pharmacol
; 931: 175189, 2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35987255
7.
Effects of microglial depletion and TREM2 deficiency on Aß plaque burden and neuritic plaque tau pathology in 5XFAD mice.
Acta Neuropathol Commun
; 9(1): 150, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503586
8.
Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines.
Sci Rep
; 10(1): 13262, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32764586
9.
Genome-wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays.
Genes Chromosomes Cancer
; 47(11): 957-64, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18663747
10.
Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons.
Eur J Pharmacol
; 858: 172474, 2019 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31238068
11.
Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome.
Clin Gastroenterol Hepatol
; 6(2): 194-205, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18237869
12.
The ontogeny of drug metabolizing enzymes and transporters in the rat.
Reprod Toxicol
; 26(3-4): 220-30, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18926897
13.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 11(2): 363-379, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30057263
14.
Chronic drug-induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell-derived cardiomyocytes.
Br J Pharmacol
; 174(21): 3766-3779, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28094846
15.
p53-independent regulation of p21Waf1/Cip1 expression and senescence by Chk2.
Mol Cancer Res
; 3(11): 627-34, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16317088
16.
Functional and Transcriptional Characterization of Histone Deacetylase Inhibitor-Mediated Cardiac Adverse Effects in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Stem Cells Transl Med
; 5(5): 602-12, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27034410
17.
MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.
Biosci Rep
; 35(6)2015 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26431963
18.
Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment.
Clin Cancer Res
; 21(14): 3327-39, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25805801
19.
Gene expression profiles highlight adaptive brain mechanisms in corticotropin releasing factor overexpressing mice.
Brain Res Mol Brain Res
; 129(1-2): 135-50, 2004 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15469890
20.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 13(2): 434-435, 2019 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31412287