Detalhe da pesquisa
1.
A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication.
RNA
; 28(2): 177-193, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34759006
2.
Positive epistasis between viral polymerase and the 3' untranslated region of its genome reveals the epidemiologic fitness of dengue virus.
Proc Natl Acad Sci U S A
; 117(20): 11038-11047, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32366663
3.
Preclinical evaluation of [18F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection.
Eur J Nucl Med Mol Imaging
; 49(13): 4516-4528, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35876869
4.
Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J Virol
; 94(21)2020 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32796069
5.
Mutations in the cytoplasmic domain of dengue virus NS4A affect virus fitness and interactions with other non-structural proteins.
J Gen Virol
; 101(9): 941-953, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589122
6.
Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication.
Int J Mol Sci
; 21(23)2020 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33291644
7.
Dengue Virus and Zika Virus Serological Cross-reactivity and Their Impact on Pathogenesis in Mice.
J Infect Dis
; 219(2): 223-233, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30085051
8.
Antiviral Candidates for Treating Hepatitis E Virus Infection.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30885901
9.
Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis.
J Virol
; 92(7)2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321322
10.
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication.
Nucleic Acids Res
; 45(22): 12904-12920, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29165589
11.
The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.
PLoS Pathog
; 12(9): e1005886, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622521
12.
Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication.
PLoS Pathog
; 12(1): e1005357, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26735137
13.
The Transactions of NS3 and NS5 in Flaviviral RNA Replication.
Adv Exp Med Biol
; 1062: 147-163, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845531
14.
Dengue Antiviral Development: A Continuing Journey.
Adv Exp Med Biol
; 1062: 319-332, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845542
15.
The Dengue Virus Replication Complex: From RNA Replication to Protein-Protein Interactions to Evasion of Innate Immunity.
Adv Exp Med Biol
; 1062: 115-129, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845529
16.
Viral Entry and NS1 as Potential Antiviral Drug Targets.
Adv Exp Med Biol
; 1062: 107-113, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845528
17.
Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5).
Proc Natl Acad Sci U S A
; 112(48): 14834-9, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578813
18.
Current Status of Dengue Therapeutics Research and Development.
J Infect Dis
; 215(suppl_2): S96-S102, 2017 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28403438
19.
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.
PLoS Pathog
; 11(3): e1004682, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25775415
20.
The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication.
J Biol Chem
; 290(4): 2379-94, 2015 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25488659