Detalhe da pesquisa
1.
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions.
Cell
; 186(18): 3793-3809.e26, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37562401
2.
Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition.
Proc Natl Acad Sci U S A
; 120(52): e2312666120, 2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38127985
3.
Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
Proc Natl Acad Sci U S A
; 119(10): e2122287119, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35238637
4.
Mechanisms by which adiponectin reverses high fat diet-induced insulin resistance in mice.
Proc Natl Acad Sci U S A
; 117(51): 32584-32593, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33293421
5.
Metabolic control analysis of hepatic glycogen synthesis in vivo.
Proc Natl Acad Sci U S A
; 117(14): 8166-8176, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32188779
6.
Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice.
J Lipid Res
; 61(12): 1565-1576, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907986
7.
Adipose glucocorticoid action influences whole-body metabolism via modulation of hepatic insulin action.
FASEB J
; 33(7): 8174-8185, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30922125
8.
Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents.
Hepatology
; 68(6): 2197-2211, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29790582
9.
In vivo studies on the mechanism of methylene cyclopropyl acetic acid and methylene cyclopropyl glycine-induced hypoglycemia.
Biochem J
; 475(6): 1063-1074, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483297
10.
Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.
Diabetologia
; 61(6): 1435-1446, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29497783
11.
Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids.
Proc Natl Acad Sci U S A
; 112(4): 1143-8, 2015 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25564660
12.
Considering the Links Between Nonalcoholic Fatty Liver Disease and Insulin Resistance: Revisiting the Role of Protein Kinase C ε.
Hepatology
; 70(6): 2217-2220, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31220350
13.
Targeting steroid receptor coactivator 1 with antisense oligonucleotides increases insulin-stimulated skeletal muscle glucose uptake in chow-fed and high-fat-fed male rats.
Am J Physiol Endocrinol Metab
; 307(9): E773-83, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25159329
14.
Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats.
Hepatology
; 57(5): 1763-72, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23175050
15.
Thyroid hormone receptor-ß agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways.
Am J Physiol Endocrinol Metab
; 305(1): E89-100, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23651850
16.
Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity.
Mol Metab
; 64: 101574, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35970449
17.
Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease.
Diabetes Care
; 44(2): 489-498, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33293347
18.
Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.
Commun Biol
; 4(1): 826, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34211098
19.
Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake.
Nat Metab
; 3(3): 378-393, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33686286
20.
Fatty Acid Esterification as a NASH Therapeutic Target.
Cell Mol Gastroenterol Hepatol
; 17(2): 311-312, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-37984466