Impact of resveratrol supplementation on clinical parameters and inflammatory markers in patients with chronic periodontitis: a randomized clinical trail.

BACKGROUND: Periodontitis is one of the most common chronic inflammatory diseases in the world, which affects oral health. Resveratrol is a polyphenol with therapeutic effects on the inflammation caused by periodontal pathogens. This study aimed to evaluate the impact of resveratrol supplementation on clinical parameters and inflammatory markers in patients with chronic periodontitis. METHODS: In this randomized, double-blind study, 40 chronic periodontitis patients underwent non-surgical therapy and were randomly assigned to two intervention and control groups, receiving either resveratrol supplements or a placebo for four weeks. Salivary levels of interleukin-8 (IL-8), interleukin-1ß (IL-1ß), and clinical parameters, including pocket depth (PD), clinical attachment level (CAL), plaque index (PI), and bleeding index (BI), were measured before and after the intervention. RESULTS: The results showed that in both the case and control groups, after four weeks of using resveratrol, only plaque index (PI) was significantly different compared to the control group (P = 0.0001). However, there were no significant differences in the mean pocket depth (PD), clinical attachment loss (CAL), bleeding index (BI), and salivary levels of IL-8 and IL-1ß between the two groups after the intervention. CONCLUSION: Resveratrol complement was helpful as an anti-inflammatory food supplement, along with other non-surgical periodontal treatments in chronic periodontitis patients.

Histological characteristics of dental pulp in teeth with periodontal problems and healthy teeth.

Background: Chronic periodontitis is the most common type of periodontitis, which is associated with calculus and plaque accumulation. Several studies have indicated that uncured periodontitis can affect the dental pulp. However, this relationship is controversial. This study aimed to compare histopathological results obtained from the dental pulp in teeth with periodontal problems and healthy teeth. Methods: In this study, 23 teeth with periodontal problems and 23 healthy teeth were extracted. After cutting off 2 mm from the root apex, the teeth were sectioned into apical, middle, and coronal thirds. Then, the specimens were evaluated in both groups based on histopathological features. Results: According to the evaluations, in the middle third, the amount of inflammation was only statistically significant in the group that consisted of teeth with periodontal problems (P=0.014). There was no significant difference in fibrosis and blood vessel diameter between the two groups. Necrosis in the middle (P=0.002) and coronal thirds (P=0.004) of teeth with periodontal problems was more than the healthy teeth. The lack of odontoblastic integrity in all the sections of teeth with periodontal problems was more than that in healthy teeth (P=0.0001). Conclusion: Inflammation of the periodontium in chronic periodontitis can lead to histological changes in the pulp, including an increase in inflammation, necrosis, and loss of odontoblastic integrity.

Evaluation of root surface roughness produced by hand instruments and ultrasonic scalers: An in vivo study.

Background. The aim of periodontal treatment is to remove bacterial plaque and dental calculus by hand and power-driven instruments. However, the comparison of the effectiveness of these instruments has always been controversial. Therefore, this in vivo study investigated and compared the effects of hand and ultrasonic piezoelectric instruments on the roughness of dental surfaces under an atomic force microscope (AFM). Methods. In this study, 35 periodontally hopeless teeth were selected and randomly divided into four groups (n=7). The control group consisted of teeth that had to be extracted for orthodontic or prosthetic treatment (n=7). In group one, scaling and root planing were performed using hand instruments. In other groups, scaling and root planing were performed using piezoelectric ultrasonic instruments with low to high power, respectively. Then the scaled teeth were extracted for analysis under an atomic force microscope. Results. This study showed that root roughness significantly differed between different experimental groups (P<0.027). The root roughness (Rq) in the SRP2 group significantly differed from the control group (P<0.05), while no significant differences were observed between the other groups. Furthermore, the least roughness was observed in the SRP3 group, with the highest roughness in the SRP2 group. Conclusion. Within the limitation of this study, there were no significant differences in surface roughness between different powers of the ultrasonic device.

The relationship between children's body mass index and periodontal status.

BACKGROUND: Childhood obesity is a serious medical condition that affects children and adolescents. Being overweight and obese are important risk factors for various adult diseases including diabetes, cardiovascular, and cerebrovascular disease, hypertension, and periodontal diseases. This study aimed to compare the periodontal findings in obese children with those exhibiting normal body mass. MATERIALS AND METHODS: In the present retrospective cohort study, 108 children, 12 years of age, were randomly assigned to the two groups with equal gender distribution, selected from the schools in Yazd, Iran: obese (body mass index [BMI] ≥25) and nonobese (BMI <25). After obtaining informed consent forms from their parents, each participant's demographic data and BMI were recorded, and periodontal indices were determined including plaque index (PI), bleeding on probing (BOP), pocket depth (PD), and clinical attachment loss (CAL). Then, a questionnaire on dietary and oral hygiene habits was completed by the participants. The data were collected and analyzed with a Chi-square test and t-test. RESULTS: The results showed statistically significantly higher mean PI, BOP, and PD in obese participants than nonobese participants (P < 0.05), with no statistically significant difference in CAL between the two groups (P > 0.05). CONCLUSIONS: The periodontal indices of PI, BOP, and PD in obese children were significantly higher than in children with a normal weight. However, there was no statistically significant difference in CAL between the two groups.

The referral pattern of patients to periodontists by general dentists / O padrão de encaminhamento de pacientes para periodontistas por clínicos gerais

Objetivo: O sucesso da terapia periodontal requer um relacionamento adequado entre o clínico geral e o periodontista. O objetivo deste estudo foi determinar, por meio de um questionário, o padrão de encaminhamento de pacientes por dentistas clínicos gerais a periodontistas em Yazd, Irã. Material e Métodos: Este estudo transversal descritivo foi realizado na forma de uma pesquisa incluindo 145 dentistas licenciados em Yazd. Foi elaborado um questionário composto por sete questões com subquestões. Resultados: 89% dos cirurgiões-dentistas encaminham o paciente ao periodontista. A recessão gengival foi o motivo mais frequente de encaminhamento (69,7%), enquanto o sangramento gengival foi o menos frequente (13,1%). Em termos de procedimentos cirúrgicos, os procedimentos mais frequentes para encaminhamentos foram terapias de periimplantite e aumento de rebordo. O encaminhamento realizado por dentistas do gênero feminino foi de 95,9% e pelo gênero masculino foi de 81,7%. O número de pacientes encaminhados por dentistas que atuavam simultaneamente em clínicas privadas e públicas foi maior do que aqueles que atuavam apenas em clínicas privadas ou públicas. O maior percentual de encaminhamento foi no grupo de cirurgiões-dentistas com menos de 5 anos de experiência, com ligeira diferença daqueles com mais de 10 anos de experiência. Apenas 26,1% dos entrevistados relataram ter participado de programas de reciclagem. Conclusão: É necessário que os dentistas gerais considerem os sinais primários da doença periodontal e encaminhem os pacientes mais graves em estágios iniciais para fornecer um resultado ideal a longo prazo para os pacientes.(AU)

Objective: The successful periodontal therapy needs a proper relationship between general dentist and periodontist. The aim of this study was to determine the referral pattern of patients to periodontists by general dentists in Yazd, Iran, by means of a questionnaire. Material and Methods: This descriptive cross-sectional study was carried out in the form of a survey among 145 licensed general dental practitioners in Yazd, Iran. A questionnaire comprising of seven questions with sub-questions was prepared. Results: 89% of dentists have referred patient to periodontist. Gingival recession was the most frequent reason for referring (69.7%) and the least was gingival bleeding (13.1%). The most frequent surgical procedure for what patients have been referred were peri-implantitis therapy and ridge augmentation. Referral status to periodontist for female dentists was 95.9% and for male dentists was 81.7%. The number of referred patients form the dentists who were practicing simultaneously at both private and public clinics was higher than those who were practicing only at private or public clinics. The most referral percentage was in the group of dentists with less than 5 years of experience with a slight difference from those with more than 10 years of experience. Only 26.1% of the respondents have participated in retraining programs. Conclusion: There is a need for general dentists to consider the primary signs of periodontal disease and necessity of referring the patients in early stages more serious, to provide an optimal long-term outcome for patients. (AU)

Evaluation of the effects of diode (980 nm) laser on gingival inflammation after nonsurgical periodontal therapy.

INTRODUCTION: Periodontitis is an inflammatory disease, for which, scaling and root planning(SRP) is the common approach for non-surgical control of inflammation. Using lasers is anotherapproach in the first phase of periodontal treatment for control of inflammation. Diode laserhas some beneficial effects such as acceleration of wound healing, promotion of angiogenesisand augmentation of growth factor release. Thus the aim of this study is the evaluation of diodelaser (980 nm) effect on gingival inflammation when it is used between the first and secondphase of periodontal treatment, in comparison with common treatment (SRP) modality alone. METHODS: In this study, 21 patients with moderate to severe chronic periodontitis were selectedand divided in to control group (SRP) and test group (SRP + laser). Two months after the lastscaling and laser radiation, indexes including gingival level (GL), bleeding on probing (BOP)and modified gingival index (MGI) were recorded and compared with baseline. RESULTS: Two months after the beginning of the study, all indices improved in both groups. Theindices were not different between two groups except for BOP which was lower in laser group. CONCLUSION: Based on overall improvement in parameters such as superiority of laser applicationin some indices, lack of thermal damage and gingival recession with the specific settings usedin this study, the application of laser as an adjunctive treatment together with common methodsis preferable.