Detalhe da pesquisa
1.
A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-ß oligomers.
J Neurochem
; 142(6): 934-947, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28670737
2.
Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station.
Yale J Biol Med
; 90(1): 45-61, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28356893
3.
Modulation of amyloid-ß aggregation by histidine-coordinating Cobalt(III) Schiff base complexes.
Chembiochem
; 15(11): 1584-9, 2014 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24961930
4.
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers.
Proc Natl Acad Sci U S A
; 106(6): 1971-6, 2009 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19188609
5.
Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease.
J Neurosci
; 27(4): 796-807, 2007 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17251419
6.
Synaptic targeting by Alzheimer's-related amyloid beta oligomers.
J Neurosci
; 24(45): 10191-200, 2004 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15537891
7.
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aß Oligomers.
PLoS One
; 10(4): e0125263, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25928376
8.
Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease.
Nat Nanotechnol
; 10(1): 91-8, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25531084
9.
Intracranial hemorrhage in systemic lupus erythematosus associated with an autoantibody against actor XIII.
Thromb Haemost
; 88(6): 919-23, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12529739
10.
Elucidating molecular mass and shape of a neurotoxic Aß oligomer.
ACS Chem Neurosci
; 5(12): 1238-45, 2014 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25343357
11.
Brain transit and ameliorative effects of intranasally delivered anti-amyloid-ß oligomer antibody in 5XFAD mice.
J Alzheimers Dis
; 35(4): 777-88, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23542865
12.
Synapse-binding subpopulations of Aß oligomers sensitive to peptide assembly blockers and scFv antibodies.
ACS Chem Neurosci
; 3(11): 972-81, 2012 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23173076
13.
A glycine zipper motif mediates the formation of toxic ß-amyloid oligomers in vitro and in vivo.
Mol Neurodegener
; 6(1): 61, 2011 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21861874
14.
Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5.
Neuron
; 66(5): 739-54, 2010 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20547131
15.
Targeting generation of antibodies specific to conformational epitopes of amyloid beta-derived neurotoxins.
CNS Neurol Disord Drug Targets
; 8(1): 65-81, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19275637
16.
Soluble state high resolution atomic force microscopy study of Alzheimer's beta-amyloid oligomers.
Appl Phys Lett
; 95(18): 183701, 2009 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19997583
17.
Detection and Identification of Bioanalytes with High Resolution LSPR Spectroscopy and MALDI Mass Spectrometry.
J Phys Chem C Nanomater Interfaces
; 113(15): 5891-5894, 2009 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20161175
18.
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.
Neurobiol Aging
; 29(9): 1334-47, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17403556
19.
Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine.
J Biol Chem
; 282(15): 11590-601, 2007 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17308309
20.
Monoclonal antibodies that target pathological assemblies of Abeta.
J Neurochem
; 100(1): 23-35, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17116235