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INTRODUCTION: Over the last few decades, the use of veno-venous extracorporeal membrane oxygenation (VV-ECMO) support for severe respiratory failure has increased. AIM: This study aimed to assess the long-term outcomes of patients treated with VV-ECMO for respiratory failure. METHODS: We performed a single-centre prospective evaluation of patients on VV-ECMO who were successfully discharged from the intensive care unit of an Italian University Hospital between January 2018 and May 2021. The enrolled patients underwent follow-up evaluations at 6 and 12 months after ICU discharge. The follow-up team performed psychological and functional assessments using the following instruments: Hospital Anxiety and Depression Scale (HADS), Post-traumatic Stress Disorder Symptom Severity Scale (PTSS-10), Euro Quality Five Domains Five Levels (EQ-5L-5D), and 6-minute walk test. RESULTS: We enrolled 33 patients who were evaluated at a follow-up clinic. The median patient age was 51 years (range: 45-58 years). The median duration of VV-ECMO support was 12 (9-19) days and the length of ICU stay was 23 (18-42) days. A HADS score higher than 14 was reported in 8 (24 %) and 7 (21 %) patients at the six- and twelve-month visit, respectively. PTSS-10 total score ≥ 35 points was present in three (9 %) and two (6 %) patients at the six- and twelve-month examination. The median EQ-5L-5D-VAS was respectively 80 (80-90) and 87.5 (70-95). The PTSS-10 score significantly decreased from six to 12 months in COVID-19 survivors (p = 0.024). CONCLUSIONS: In this cohort of patients treated with VV-ECMO, cognitive and psychological outcomes were good and comparable to those of patients with Adult Respiratory Distress Syndrome (ARDS) managed without ECMO. IMPLICATIONS FOR CLINICAL PRACTICE: The findings of this study confirm the need for long-term follow-up and rehabilitation programs for every ICU survivor after discharge. COVID-19 survivors treated with VV-ECMO had outcomes comparable to those reported in non-COVID patients.
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COVID-19 , Oxigenação por Membrana Extracorpórea , Insuficiência Respiratória , Transtornos de Estresse Pós-Traumáticos , Humanos , Pessoa de Meia-Idade , Oxigenação por Membrana Extracorpórea/psicologia , Unidades de Terapia Intensiva , Estudos Retrospectivos , Transtornos de Estresse Pós-Traumáticos/terapiaRESUMO
INTRODUCTION: Limited data is available regarding the incidence of pressure injuries in patients who have undergone Extracorporeal Membrane Oxygenation (ECMO), a life-saving technique that provides respiratory support for hypoxemia that does not respond to conventional treatment. AIM: To assess the incidence of pressure injuries and identify the risk factors in Acute Respiratory Distress Syndrome patients receiving ECMO. METHODS: A retrospective observational study utilizing prospectively collected data was performed in an Italian intensive care unit, between 1 January 2012 and 30 April 2022 enrolling all consecutive patients with Acute Respiratory Distress Syndrome who underwent ECMO. RESULTS: One hundred patients were included in this study. 67 patients (67%) developed pressure injuries during their intensive care unit stay, with a median of 2 (1-3) sites affected. The subgroup of patients with pressure injuries was more hypoxic before ECMO implementation, received more frequent continuous renal replacement therapy and prone positioning, and showed prolonged ECMO duration, intensive care unit and hospital length of stay compared to patients without pressure injuries. The logistic model demonstrated an independent association between the pO2/FiO2 ratio prior to ECMO initiation, the utilization of the prone positioning during ECMO, and the occurrence of pressure injuries. CONCLUSIONS: The incidence of pressure injuries was elevated in patients with Adult Respiratory Distress Syndrome who received ECMO. The development of pressure injuries was found to be independently associated with hypoxemia before ECMO initiation and the utilization of prone positioning during ECMO. IMPLICATIONS FOR CLINICAL PRACTICE: Patients who require ECMO for respiratory failure are at a high risk of developing pressure injuries. To ensure optimal outcomes during ECMO implementation and treatment, it is vital to implement preventive measures and to closely monitor skin health in at-risk areas.
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Oxigenação por Membrana Extracorpórea , Úlcera por Pressão , Síndrome do Desconforto Respiratório , Insuficiência Respiratória , Adulto , Humanos , Respiração Artificial/métodos , Estudos Retrospectivos , Oxigenação por Membrana Extracorpórea/efeitos adversos , Oxigenação por Membrana Extracorpórea/métodos , Úlcera por Pressão/epidemiologia , Úlcera por Pressão/etiologia , Fatores de Risco , Insuficiência Respiratória/complicações , Insuficiência Respiratória/epidemiologia , Síndrome do Desconforto Respiratório/complicações , Síndrome do Desconforto Respiratório/epidemiologia , Hipóxia/complicações , Hipóxia/terapiaRESUMO
Introducción: la residencia médica es un sistema formativo cuya principal finalidad es educar al médico, brindándole las herramientas necesarias para un óptimo proceso de formación durante su especialización. Objetivo: identificar las características del residentado médico en tres sedes docentes de Lima, Perú. Métodos: se realizó un estudio descriptivo transversal en tres sedes docentes de Lima, durante el mes de marzo de 2015. A los médicos residentes de cada sede se les aplicó una encuesta estructurada en tres secciones: datos generales, características laborales y características académicas de su programa de residentado. Resultados: la edad promedio fue 29,4 ± 3,4 y el 31 por ciento fue de sexo masculino. Solo el 57,1 por ciento refirió que le tomaron exámenes ocupacionales y la mayoría de los residentes no recibía alimentación en sus sedes. El 74,3 por ciento y 7,1 por ciento de los residentes indicó recibir capacitación en metodología de la investigación y salud ocupacional, de manera respectiva, pero en su mayoría no fueron calificadas como buenas. Conclusiones: existen ciertos déficits en el actual proceso de formación de los médicos residentes, sobre todo en aspectos relacionados a la prevención de riesgos ocupacionales, condiciones laborales y de infraestructura, y la promoción de la investigación(AU)
Introduction: The medical residency is an educational system whose main purpose is to educate the physician, providing the necessary tools for an optimal training process during their specialization. Objective: To identify the characteristics of medical residency in three teaching centers in Lima, Peru. Methods: We conducted a cross sectional descriptive study in three teaching centers in Lima during March 2015. A structured survey was applied in medical residents. The survey had three sections: General data, job characteristics and academic characteristics of their medical residency. Results: The mean age was 29.4 ± 3.4 and 31 percent were male. Occupational examinations were only taken in 57.1 pecent and most residents did not receive food in their centers. The 74.3 percent and 7.1 percent of residents reported receiving training in research methodology and occupational health respectively. However, both trainings were not rated as good by most of them. Conclusion: There are certain gaps in the ongoing training of medical residents, mainly on issues related to the prevention of occupational risks, working and infrastructure conditions, and research promotion(AU)
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Humanos , Masculino , Adulto , Especialização , Características de Residência , Educação Médica/tendências , Capacitação Profissional , Docentes , Estudos Transversais , Estudo ObservacionalRESUMO
OBJETIVO: Describir el estado nutricional de niños de 6 a 10 años, de la Comunidad de Niños ôSagrada Familiaõ de Lima-Perú, durante marzo 2011. MATERIAL Y MÉTODO: Estudio descriptivo, transversal y prospectivo. Se estudió a 126 niños y niñas entre 6 y 10 años. Se consideró como variables: peso, talla e IMC. Para los diagnósticos de malnutrición se utilizaron: índices de Peso/edad, Talla/edad e IMC/edad, según el criterio actual de la OMS. Se determinó el valor ôzõ mediante programa OMS-AnthroPlus v1.0.4. El análisis de datos se realizó con el programa SPSS v15.0. RESULTADOS: 73% hombres y 27% mujeres, la mayoría tenían 10 años (29,4%). La media de peso, talla e IMC fueron 25,23 kg; 122,14 cm y 16,82 kg/m2. En cuanto al diagnóstico nutricional; 5,6% de niños presentaron desnutrición global, 23,8% desnutrición crónica, 21,4% sobrepeso y 2,4% obesidad, los hombres presentaron mayor porcentaje de desnutrición global (7,7%), desnutrición crónica (27,5%) y sobrepeso (23,1%), en cambio las mujeres presentaron mayor porcentaje de obesidad (2,9%). 71,4% de niños con desnutrición global eran desnutridos crónicos, 22,2% con sobrepeso poseían desnutrición crónica y 100% de obesos tenían crecimiento normal. CONCLUSIONES: El diagnóstico de malnutrición con mayor prevalencia es la desnutrición crónica. Además, se encontró solo casos de desnutridos crónicos con sobrepeso. Por tanto, a pesar que la desnutrición crónica está disminuyendo, no evita que sea la de mayor prevalencia a nivel escolar.
OBJETIVE: To describe the nutritional status of children from 6 to 10 years of age in the ôSagrada Familiaõ child community in Lima, Perú, in March 2011. MATERIALS AND METHOD: Type of study is descriptive, transversal and prospective. We studied 126 children between 6 and 10 years of the ôSagrada Familiaõchild community. The variables considered were weight, height and BMI as well as the diagnosis of malnutrition rates using weight / age, height / age and BMI / age current WHO criteria. We determined the value ôzõ using WHO-AnthroPlus v1.0.4. Data analysis was performed using SPSS v15.0. RESULTS: 73% were male and 27% female, most were 10 years of age (29.4%). Mean weight, height and BMI were 25.23 kg, 122.14 cm and 16.82 kg/m2 respectively. As for the nutritional diagnosis, 5.6% of children had global malnutrition, 23.8% had chronic malnutrition, 21.4% were overweight and 2.4% obese, males had a higher percentage of global malnutrition (7.7%), chronic malnutrition (27.5%) and overweight (23.1%), whereas women had a higher percentage of obesity (2.9%). 71.4% of children with global malnutrition had chronic malnutrition, 22.2% who were overweight had chronic malnutrition, and 100 % of obese have normal growth. CONCLUSIONS: The diagnosis of malnutrition is most prevalent as chronic malnutrition. It was also found only cases of chronically undernourished with overweight. Therefore, although chronic malnutrition is declining, it doesn´t stop being the most prevalent at school level.