Detalhe da pesquisa
1.
Phospholipase A2 receptor 1 promotes lung cell senescence and emphysema in obstructive lung disease.
Eur Respir J
; 58(2)2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33509955
2.
PLA2R1: expression and function in cancer.
Biochim Biophys Acta
; 1846(1): 40-4, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24667060
3.
[New physiopathological roles for the PLA2R1 receptor in cancer and membranous nephropathy]. / Nouveaux rôles physiopathologiques pour le récepteur PLA2R1 dans le cancer et la glomérulonéphrite extramembraneuse.
Med Sci (Paris)
; 30(5): 519-25, 2014 May.
Artigo
em Francês
| MEDLINE | ID: mdl-24939538
4.
Targeting chemoresistant senescent pancreatic cancer cells improves conventional treatment efficacy.
Mol Biomed
; 4(1): 4, 2023 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36739330
5.
Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema.
Aging (Albany NY)
; 15(23): 13581-13592, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38095616
6.
Loss of Pla2r1 decreases cellular senescence and age-related alterations caused by aging and Western diets.
Aging Cell
; 22(11): e13971, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37667516
7.
Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells.
Cancer Lett
; 546: 215850, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35926818
8.
NF-κB-dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells.
Aging Cell
; 21(7): e13632, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35653631
9.
Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis.
Cancer Cell Int
; 11: 42, 2011 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22136382
10.
PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging.
Cell Death Dis
; 12(2): 190, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33594040
11.
Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging.
Nat Commun
; 12(1): 720, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33526781
12.
Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1.
Sci Rep
; 10(1): 8190, 2020 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424163
13.
Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
Aging Cell
; 17(6): e12835, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30216637
14.
The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway.
Aging Cell
; 17(3): e12736, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29446526
15.
mTOR pathway activation drives lung cell senescence and emphysema.
JCI Insight
; 3(3)2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29415880
16.
Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution.
Oncotarget
; 7(22): 32100-12, 2016 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050073
17.
Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program.
Aging (Albany NY)
; 7(11): 986-1003, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26583757
18.
Identification of tumor necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL) and its receptors in adult rat ventral prostate.
Mol Cell Endocrinol
; 198(1-2): 115-21, 2002 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-12573821
19.
Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence.
Nat Commun
; 5: 3792, 2014 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24797322
20.
MUC1 drives epithelial-mesenchymal transition in renal carcinoma through Wnt/ß-catenin pathway and interaction with SNAIL promoter.
Cancer Lett
; 346(2): 225-36, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24384091