Detalhe da pesquisa
1.
Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice.
Proc Natl Acad Sci U S A
; 119(50): e2214396119, 2022 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36472957
2.
Amino acid residues at core protein dimer-dimer interface modulate multiple steps of hepatitis B virus replication and HBeAg biogenesis.
PLoS Pathog
; 17(11): e1010057, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34752483
3.
BMaps: A Web Application for Fragment-Based Drug Design and Compound Binding Evaluation.
J Chem Inf Model
; 63(14): 4229-4236, 2023 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406353
4.
A putative amphipathic alpha helix in hepatitis B virus small envelope protein plays a critical role in the morphogenesis of subviral particles.
J Virol
; 95(8)2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33536177
5.
4-Oxooctahydroquinoline-1(2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators.
Bioorg Med Chem Lett
; 58: 128518, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34979256
6.
Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal.
J Chem Inf Model
; 54(10): 2816-25, 2014 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25263519
7.
Identification of novel tetrahydroquinoxaline derived phenyl ureas as modulators of the hepatitis B virus nucleocapsid assembly.
Eur J Med Chem
; 259: 115634, 2023 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37499290
8.
Modeling nonaqueous proton wires built from helical peptides: biased proton transfer driven by helical dipoles.
J Phys Chem A
; 116(4): 1283-8, 2012 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22188565
9.
Modeling energy landscapes of proton motion in nonaqueous, tethered proton wires.
J Phys Chem A
; 115(21): 5423-34, 2011 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21553870
10.
Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators.
Antiviral Res
; 191: 105080, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33933516
11.
Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B.
Antiviral Res
; 182: 104917, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818519
12.
Profiling the circulating mRNA transcriptome in human liver disease.
Oncotarget
; 11(23): 2216-2232, 2020 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32577166
13.
Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist.
ACS Infect Dis
; 5(7): 1139-1149, 2019 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31060350
14.
CpAMs induce assembly of HBV capsids with altered electrophoresis mobility: Implications for mechanism of inhibiting pgRNA packaging.
Antiviral Res
; 159: 1-12, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30201396
15.
Importance of dynamic hydrogen bonds and reorientation barriers in proton transport.
Chem Commun (Camb)
; 47(23): 6638-40, 2011 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21547306