Detalhe da pesquisa
1.
Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth.
J Biol Chem
; 299(1): 102766, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36470425
2.
Sinularamides A-G, Terpenoid-Derived Spermidine and Spermine Conjugates with Casitas B-Lineage Lymphoma Proto-Oncogene B (Cbl-b) Inhibitory Activities from a Sinularia sp. Soft Coral.
J Nat Prod
; 84(6): 1831-1837, 2021 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34038132
3.
Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana.
Mar Drugs
; 19(7)2021 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34202500
4.
Suberitamides A-C, Aryl Alkaloids from a Pseudosuberites sp. Marine Sponge that Inhibit Cbl-b Ubiquitin Ligase Activity.
Mar Drugs
; 18(11)2020 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33126420
5.
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.
Breast Cancer Res Treat
; 155(2): 235-51, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26759246
6.
Targeting Mitochondria with ClpP Agonists as a Novel Therapeutic Opportunity in Breast Cancer.
Cancers (Basel)
; 15(7)2023 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37046596
7.
Thymidylate synthase as an oncogene: a novel role for an essential DNA synthesis enzyme.
Cancer Cell
; 5(4): 341-51, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15093541
8.
Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL-B.
Org Lett
; 24(51): 9468-9472, 2022 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36516994
9.
Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis.
Cancer Res Commun
; 2(10): 1144-1161, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36388465
10.
In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors.
SLAS Discov
; 26(7): 870-884, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33882749
11.
Cbl interacts with multiple E2s in vitro and in cells.
PLoS One
; 14(5): e0216967, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31120930
12.
ONC201 kills breast cancer cells in vitro by targeting mitochondria.
Oncotarget
; 9(26): 18454-18479, 2018 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29719618
13.
CRKL mediates EML4-ALK signaling and is a potential therapeutic target for ALK-rearranged lung adenocarcinoma.
Oncotarget
; 7(20): 29199-210, 2016 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27078848
14.
LAMC2 enhances the metastatic potential of lung adenocarcinoma.
Cell Death Differ
; 22(8): 1341-52, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25591736
15.
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.
Nat Genet
; 46(8): 844-9, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24974848
16.
Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors.
Clin Cancer Res
; 19(8): 1960-71, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23444221
17.
Whole genome and transcriptome sequencing of a B3 thymoma.
PLoS One
; 8(4): e60572, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23577124
18.
MicroRNA expression and clinical outcome of small cell lung cancer.
PLoS One
; 6(6): e21300, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21731696
19.
Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent.
Cell Cycle
; 10(23): 4074-82, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22101337
20.
Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A.
Int J Oncol
; 37(4): 963-71, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20811718