Detalhe da pesquisa
1.
NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs.
Cell
; 186(13): 2783-2801.e20, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37267949
2.
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Cell
; 184(1): 149-168.e17, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33278357
3.
CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer's disease pathology.
Nat Immunol
; 24(10): 1735-1747, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679549
4.
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Cell
; 181(3): 674-687.e13, 2020 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32298652
5.
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Nat Immunol
; 22(7): 829-838, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33963333
6.
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.
Cell
; 162(1): 45-58, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26095253
7.
Necroptosis blockade prevents lung injury in severe influenza.
Nature
; 628(8009): 835-843, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38600381
8.
Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis.
Nat Immunol
; 17(3): 277-85, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26808230
9.
Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.
Immunity
; 51(6): 1012-1027.e7, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31668641
10.
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.
Nat Immunol
; 16(2): 178-87, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25559258
11.
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
Nat Immunol
; 16(5): 467-75, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25774715
12.
SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.
Immunity
; 49(3): 515-530.e5, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30231985
13.
Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.
Immunity
; 49(5): 899-914.e6, 2018 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30413360
14.
Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity.
Immunity
; 49(3): 531-544.e6, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30170813
15.
Lipid signalling enforces functional specialization of Treg cells in tumours.
Nature
; 591(7849): 306-311, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33627871
16.
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity.
Nature
; 600(7888): 308-313, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34795452
17.
ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.
Mol Cell
; 74(4): 742-757.e8, 2019 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30979586
18.
Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.
Immunity
; 46(4): 635-648, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28410990
19.
Galactosaminogalactan activates the inflammasome to provide host protection.
Nature
; 588(7839): 688-692, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268895
20.
Exuberant fibroblast activity compromises lung function via ADAMTS4.
Nature
; 587(7834): 466-471, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33116313