Detalhe da pesquisa
1.
In vitro safety signals for potential clinical development of the anti-inflammatory pregnane X receptor agonist FKK6.
Bioorg Chem
; 144: 107137, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38245951
2.
Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor That Induces CYP1A1 in Hepatic and Intestinal Cells.
Int J Mol Sci
; 21(8)2020 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32316498
3.
Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization.
Int J Mol Sci
; 21(7)2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283770
4.
Belinostat, at Its Clinically Relevant Concentrations, Inhibits Rifampicin-Induced CYP3A4 and MDR1 Gene Expression.
Mol Pharmacol
; 95(3): 324-334, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30622215
5.
A study of micronized poloxamers as lubricants in direct compression of tablets.
Acta Pol Pharm
; 70(6): 1087-96, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24383332
6.
Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice.
Nat Commun
; 14(1): 2728, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37169746
7.
Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells.
Cancers (Basel)
; 14(17)2022 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36077780
8.
Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.
J Med Chem
; 65(9): 6859-6868, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35416668
9.
Differential activation of human pregnane X receptor PXR by isomeric mono-methylated indoles in intestinal and hepatic in vitro models.
Toxicol Lett
; 324: 104-110, 2020 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32092453
10.
Indole microbial intestinal metabolites expand the repertoire of ligands and agonists of the human pregnane X receptor.
Toxicol Lett
; 334: 87-93, 2020 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33002526
11.
Targeting the pregnane X receptor using microbial metabolite mimicry.
EMBO Mol Med
; 12(4): e11621, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32153125
12.
Mono-methylindoles induce CYP1A genes and inhibit CYP1A1 enzyme activity in human hepatocytes and HepaRG cells.
Toxicol Lett
; 313: 66-76, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31201936