Multispectral stealth multilayer etched film structure based on ultrathin silver.

Spontaneous infrared radiation dissipation is a critical factor in facilitating object cooling, which influences the thermal stability and stealth efficacy of infrared stealth devices. Furthermore, the compatibility between efficient visible, infrared, and radar stealth is challenging due to different camouflage principles in different bands. This Letter presents a five-layer etched film structure to achieve multispectral stealth, and the utilization of the high-quality ultrathin silver films enables highly efficient infrared selective emission. This etched film structure with few layers demonstrates potential applications in diverse domains, including multi-band anti-detection and multispectral manipulation.

Optically transparent and microwave diffusion coding metasurface by utilizing ultrathin silver films.

The past few years have witnessed the great success of artificial metamaterials with effective medium parameters to control electromagnetic waves. Herein, we present a scheme to achieve broadband microwave low specular reflection with uniform backward scattering by using a coding metasurface, which is composed of a rational layout of subwavelength coding elements, via an optimization method. We propose coding elements with high transparency based on ultrathin doped silver, which are capable of generating large phase differences (∼180°) over a wide frequency range by designing geometric structures. The electromagnetic diffusion of the coding metasurface originates from the destructive interference of the reflected waves in various directions. Numerical simulations and experimental results demonstrate that low reflection is achieved from 12 to 18 GHz with a high angular insensitivity of up to ±40° for both transverse electric and transverse magnetic polarizations. Furthermore, the excellent visible transparency of the encoding metasurface is promising for various microwave and optical applications such as electronic surveillance, electromagnetic interference shielding, and radar cross-section reduction.

Systematic Comparison and Comprehensive Evaluation of 80 Amino Acid Descriptors in Peptide QSAR Modeling.

The peptide quantitative structure-activity relationship (QSAR), also known as the quantitative sequence-activity model (QSAM), has attracted much attention in the bio- and chemoinformatics communities and is a well developed computational peptidology strategy to statistically correlate the sequence/structure and activity/property relationships of functional peptides. Amino acid descriptors (AADs) are one of the most widely used methods to characterize peptide structures by decomposing the peptide into its residue building blocks and sequentially parametrizing each building block with a vector of amino acid principal properties. Considering that various AADs have been proposed over the past decades and new AADs are still emerging today, we herein query the following: is it necessary to develop so many AADs and do we need to continuously develop more new AADs? In this study, we exhaustively collect 80 published AADs and comprehensively evaluate their modeling performance (including fitting ability, internal stability, and predictive power) on 8 QSAR-oriented peptide sample sets (QPSs) by employing 2 sophisticated machine learning methods (MLMs), totally building and systematically comparing 1280 (80 AADs × 8 QPSs × 2 MLMs) peptide QSAR models. The following is revealed: (i) None of the AADs can work best on all or most peptide sets; an AAD usually performs well for some peptides but badly for others. (ii) Modeling performance is primarily determined by the peptide samples and then the MLMs used, while AADs have only a moderate influence on the performance. (iii) There is no essential difference between the modeling performances of different AAD types (physiochemical, topological, 3D-structural, etc.). (iv) Two random descriptors, which are separately generated randomly in standard normal distribution N(0, 1) and uniform distribution U(-1, +1), do not perform significantly worse than these carefully developed AADs. (v) A secondary descriptor, which carries major information involved in the 80 (primary) AADs, does not perform significantly better than these AADs. Overall, we conclude that since there are various AADs available to date and they already cover numerous amino acid properties, further development of new AADs is not an essential choice to improve peptide QSAR modeling; the traditional AAD methodology is believed to have almost reached the theoretical limit nowadays. In addition, the AADs are more likely to be a vector symbol but not informative data; they are utilized to mark and distinguish the 20 amino acids but do not really bring much original property information to these amino acids.

Correction to: The role of high load herpes simplex virus in patients with mechanical ventilation: a real hospital acquired viral lung infection needs antiviral therapy?

An amendment to this paper has been published and can be accessed via the original article.

High-transmittance double-layer frequency-selective surface based on interlaced multiring metallic mesh.

In this work, we proposed an optically transparent double-layer frequency-selective surface (FSS) based on interlaced multiring metallic mesh. By changing the large metal area of a conventional double-layer FSS into triangular-orthogonal distributed basic rings and nested rotated subrings, we achieved an FSS with high optical transmittance and low normalized high-order diffraction intensity while maintaining a flat passband and steep transition band. The results showed that our fabricated FSS had a normalized visible transmittance of 90.31%, stable filtering passband of ∼33.9 GHz, 3 dB bandwidth of 13.4 GHz, and uniform diffraction distribution, which are favorable characteristics for optically transparent FSS applications.

Double-layer interlaced nested multi-ring array metallic mesh for high-performance transparent electromagnetic interference shielding.

We report a nested multi-ring array metallic mesh (NMA-MM) that shows a highly uniform diffraction pattern theoretically and experimentally. Then a high-performance transparent electromagnetic interference (EMI) shielding structure is constituted by the double-layer interlaced NMA-MMs separated by transparent quartz-glass substrate. Experimental results show that double-layer interlaced NMA-MM structure exhibits a shielding effectiveness (SE) of over 27 dB in the Ku-band, with a maximal SE of 37 dB at 12 GHz, normalized optical transmittance of 90%, and minimal image quality degradation due to the interlaced arrangement. It thus shows great potential for practical applications in transparent EMI shielding devices.

[Comparative analysis on industrial standardization degree of Chinese and Korean ginseng].

Panax ginseng is a well-known medicinal plant all over the world. It has high nutritional value and medicinal value. China and South Korea are the major countries in the world for ginseng cultivation, production and exportation. China's ginseng production accounts for more than half of the world, but the output value is less than that of Korea. The standardization process of ginseng industry plays an important role. This paper makes a detailed analysis of the Chinese and Korean ginseng national standards and the standardization process, and makes a detailed comparative analysis of the categories, standard contents, index selection, age, implementation and promotion status of the Chinese and Korean ginseng standards. The development disadvantages of ginseng industry standardization were displayed. And we give our advises on the standard revision, implementation of China's ginseng industry standardization, hoping to enhance the competitiveness of China's ginseng industry.

Generation of uniform diffraction pattern and high EMI shielding performance by metallic mesh composed of ring and rotated sub-ring arrays.

We present an optical transmission model and a fast shielding effectiveness (SE) evaluation method for the inductive mesh comprising metallic rings with rotated sub-ring arrays, which can be extended for designing and optimizing other ring-based mesh structures. The theoretical analysis and experimental verification show that the established model and method are valid. A Ku-band SE >17 dB (98% energy attenuation) is observed for a triangular ring mesh with rotated sub-rings, and a normalized visible transmittance >95% is obtained with an ultra-uniform diffraction pattern, thus indicating the possibilities of our approach for high-optical-transmittance, strong-SE, reduced-image-degradation shielding applications.

Optically transparent frequency selective surface based on nested ring metallic mesh.

An optically transparent frequency selective surface (FSS) based on a nested ring metallic mesh is proposed, whose diffraction distribution is uniform and normalized higher-order diffraction intensity is lower than that of an existing transparent FSS based on metallic meshes. Compared with non-meshed FSSs, the proposed FSS has a remarkably higher optical transmittance, lower -3 dB bandwidth, and higher maximum transmittance in the microwave band. Experimental results indicate that the FSS sample achieved a normalized visible transmittance of 94.84%, uniform diffraction distribution, and stable filtering passband around 31.00 GHz simultaneously, which are attractive properties for transparent FSS applications.

Achieving an ultra-uniform diffraction pattern of stray light with metallic meshes by using ring and sub-ring arrays.

We provide theoretical and experimental evidence that introducing metallic rings and sub-rings in mesh unit cells significantly decreases the high-order diffraction energy. Moreover, rotating the sub-rings results in increased uniformity in the diffraction distribution without affecting the transmittance. Experiments show that the triangular ring mesh with rotated sub-rings exhibits a normalized visible transmittance greater than 95% as well as an ultra-uniform diffraction pattern of stray light, whose maximal normalized high-order diffraction energy is lower than 0.0167%. This kind of metallic mesh will be favorable in transparent electromagnetic interference shielding devices and touch screens.

Verification and improvement of equivalent refractive index models for evaluating the shielding effectiveness of high-transmittance double-layer metallic meshes.

The validity of real and complex equivalent refractive index models (ERIMs) is verified for a shielding effectiveness evaluation of high-transmittance double-layer metallic meshes. Theoretical and experimental studies show that the real ERIM is invalid for thin substrates and inaccurate for thick substrates for double-layer meshes, although it has long been used successfully for single-layer meshes. However, the complex ERIM shows more reasonable results not only for double-layer but also for single-layer meshes, and the evaluation accuracy is further improved by modifying the equivalent reactance coefficient using least-squares fitting. Therefore, the modified complex ERIM is applicable in most conditions.

A visible-near-infrared transparent miniaturized frequency-selective metasurface with a microwave transmission window.

In this work, we propose a meshed miniaturized frequency-selective metasurface (MMFSM), which is insensitive to the incidence microwave angle and has great optical imaging quality by extending the effective length of the aperture within the periodic unit and replacing large metal parts with different metallic meshes. Experimental results indicated that our MMFSM had an average normalized transmittance of 87.2% in the visible-near-infrared band, a passband loss of 1.446 dB, and an oblique incidence stabilization angle of 50° (the passband loss was less than 2.38 dB). These are excellent characteristics required for applications in the optics and communication fields.

ZmWRKY70 activates the expression of hypoxic responsive genes in maize and enhances tolerance to submergence in Arabidopsis.

Hypoxic stress due to submergence is a serious threat to the growth and development of maize. WRKY transcription factors are significant regulators of plant responses to various abiotic and biotic stresses. Nevertheless, their function and regulatory mechanisms in the resistance of maize to submergence stress remain unclear. Here we report the cloning of a maize WRKY transcription factor gene, ZmWRKY70, transcripts of which accumulate under submergence stress in maize seedlings. Subcellular localization analysis and yeast transcriptional activation assay indicated that ZmWRKY70 was localized in the nucleus and had transcriptional activation activity. Heterologous overexpression of ZmWRKY70 in Arabidopsis increased the tolerance of seeds and seedlings to submergence stress by upregulating the transcripts of several key genes involved in anaerobic respiration, such as group VII ethylene-responsive factor (ERFVII) (AtRAP2.2), alcohol dehydrogenase (AtADH1), pyruvate decarboxylase (AtPDC1/2), and sucrose synthase (AtSUS4), under submergence conditions. Moreover, the overexpression of ZmWRKY70 in maize mesophyll protoplasts enhanced the expression of ZmERFVII members (ZmERF148, ZmERF179, and ZmERF193), ZmADH1, ZmPDC2/3, and ZmSUS1. Yeast one-hybrid and dual-luciferase activity assays further confirmed that ZmWRKY70 enhanced the expression of ZmERF148 by binding to the W box motif located in the promoter region of ZmERF148. Together, these results indicate that ZmWRKY70 plays a significant role in tolerance of submergence stress. This work provides a theoretical basis, and suggests excellent genes, for biotechnological breeding to improve the tolerance of maize to submergence through the regulation of ZmWRKY genes.

Should we initiate vasopressors earlier in patients with septic shock: A mini systemic review.

Septic shock treatment remains a major challenge for intensive care units, despite the recent prominent advances in both management and outcomes. Vasopressors serve as a cornerstone of septic shock therapy, but there is still controversy over the timing of administration. Specifically, it remains unclear whether vasopressors should be used early in the course of treatment. Here, we provide a systematic review of the literature on the timing of vasopressor administration. Research was systematically identified through PubMed, Embase and Cochrane searching according to PRISMA guidelines. Fourteen studies met the eligibility criteria and were included in the review. The pathophysiological basis for early vasopressor use was classified, with the exploration on indications for the early administration of mono-vasopressors or their combination with vasopressin or angiotensinII. We found that mortality was 28.1%-47.7% in the early vasopressors group, and 33.6%-54.5% in the control group. We also investigated the issue of vasopressor responsiveness. Furthermore, we acknowledged the subsequent challenge of administration of high-dose norepinephrine via peripheral veins with early vasopressor use. Based on the literature review, we propose a possible protocol for the early initiation of vasopressors in septic shock resuscitation.