Quaternary Ammonium Groups Modified Magnetic Cyclodextrin Polymers for Highly Efficient Dye Removal and Sterilization in Water Purification.

Water recovery is a significant proposition for human survival and sustainable development, and we never stop searching for more efficient, easy-operating, low-cost and environmentally friendly methods to decontaminate water bodies. Herein, we combined the advantages of ß-cyclodextrin (ß-CD), magnetite nanoparticles (MNs), and two kinds of quaternary ammonium salts to synthesize two porous quaternary ammonium groups capped magnetic ß-CD polymers (QMCDP1 and QMCDP2) to remove organic pollutants and eradicate pathogenic microorganisms effectively through a single implementation. In this setting, ß-CD polymer (CDP) was utilized as the porous substrate material, while MNs endowed the materials with excellent magnetism enhancing recyclability in practical application scenarios, and the grafting of quaternary ammonium groups was beneficial for the adsorption of anionic dyes and sterilization. Both QMCDPs outperformed uncapped MCDPs in their adsorption ability of anionic pollutants, using methyl blue (MB) and orange G (OG) as model dyes. Additionally, QMCDP2, which was modified with longer alkyl chains than QMCDP1, exhibits superior bactericidal efficacy with a 99.47% removal rate for Staphylococcus aureus. Accordingly, this study provides some insights into designing a well-performed and easily recyclable adsorbent for simultaneous sterilization and adsorption of organic contaminants in wastewater.

Cyclodextrin regulated natural polysaccharide hydrogels for biomedical applications-a review.

Cyclodextrin and its derivative (CDs) are natural building blocks for linking with other components to afford functional biomaterials. Hydrogels are polymer network systems that can form hydrophilic three-dimensional network structures through different cross-linking methods and are developing as potential materials in biomedical applications. Natural polysaccharide hydrogels (NPHs) are widely adopted in biomedical field with good biocompatibility, biodegradability, low cytotoxicity, and versatility in emulating natural tissue properties. Compared with conventional NPHs, CD regulated natural polysaccharide hydrogels (CD-NPHs) maintain good biocompatibility, while improving poor mechanical qualities and unpredictable gelation times. Recently, there has been increasing and considerable usage of CD-NPHs while there is still no review comprehensively introducing their construction, classification, and application of these hydrogels from the material point of view regarding biomedical fields. To draw a complete picture of the current and future development of CD-NPHs, we systematically overview the classification of CD-NPHs, and provide a holistic view on the role of CD-NPHs in different biomedical fields, especially in drug delivery, wound dressing, cell encapsulation, and tissue engineering. Moreover, the current challenges and prospects of CD-NPHs are discussed rationally, providing an insight into developing vibrant fields of CD-NPHs-based biomedicine, and facilitating their translation from bench to clinical medicine.

Thiol-ene photoclick reaction: An eco-friendly and facile approach for preparation of MPEG-g-keratin biomaterial.

Wool keratin is a natural material with excellent properties, which is considered as scaffold biomaterial for tissue engineering. Polyethylene glycol can improve the mechanical properties of keratin materials because of its excellent biocompatibility and plasticity. In the present work, poly (ethylene glycol) methyl ether methacrylate (MPEGMA) was grafted onto keratin by thiol-ene photoclick reaction. The results of FTIR and SDS-PAGE verified the successful reaction between MPEGMA and keratin. Compared with the keratin, circular dichroism and XRD results showed that the ß-sheet ratio increased in MPEG-g-keratin. Additionally, it can be found that the exposure of keratin hydrophobic amino acids increased quickly and the micelle size became larger due to the introduction of MPEG from the results of fluorescence spectroscopy and particle size analysis. The MPEG-g- keratin was formed into a membrane to further study the application of the modified keratin. Compared with the keratin membrane, the flexibility and biocompatibility of modified keratin have been improved. This work provides an eco-friendly and facile approach for preparation of the keratin biomaterials.