Detalhe da pesquisa
1.
DNA nanomachines reveal an adaptive energy mode in confinement-induced amoeboid migration powered by polarized mitochondrial distribution.
Proc Natl Acad Sci U S A
; 121(14): e2317492121, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38547056
2.
PRMT5-mediated homologous recombination repair is essential to maintain genomic integrity of neural progenitor cells.
Cell Mol Life Sci
; 81(1): 123, 2024 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38459149
3.
Computer-directed rational design enhanced the thermostability of carbonyl reductase LsCR for the synthesis of ticagrelor precursor.
Biotechnol Bioeng
; 121(5): 1532-1542, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38265115
4.
Disruption of a kasB homolog gene (kasB) causes attenuation of cell invasion and virulence of Nocardia seriolae.
J Fish Dis
; 47(3): e13896, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38054569
5.
Lamin A/C and Vimentin as a Coordinated Regulator during Amoeboid Migration in Microscale Confined Microenvironments.
Nano Lett
; 23(14): 6727-6735, 2023 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37459599
6.
Escaping Behavior of Sperms on the Biomimetic Oviductal Surface.
Anal Chem
; 95(4): 2366-2374, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36655581
7.
Vaccinia virus induces EMT-like transformation and RhoA-mediated mesenchymal migration.
J Med Virol
; 95(8): e29041, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37621182
8.
Strategies for tailoring pH performances of glycoside hydrolases.
Crit Rev Biotechnol
; 43(1): 121-141, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34865578
9.
Recent advances in structure-based enzyme engineering for functional reconstruction.
Biotechnol Bioeng
; 120(12): 3427-3445, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638646
10.
Structural-guided design to improve the catalytic performance of aldo-keto reductase KdAKR.
Biotechnol Bioeng
; 120(12): 3543-3556, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37641876
11.
Coevolving stability and activity of LsCR by a single point mutation and constructing neat substrate bioreaction system.
Biotechnol Bioeng
; 120(6): 1521-1530, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36799475
12.
In Situ Single-Molecule Imaging of MicroRNAs in Switchable Migrating Cells under Biomimetic Confinement.
Anal Chem
; 94(9): 4030-4038, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213802
13.
Ultrasensitive Trace Sample Proteomics Unraveled the Protein Remodeling during Mesenchymal-Amoeboid Transition.
Anal Chem
; 94(2): 768-776, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34928127
14.
Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.
PLoS Biol
; 17(10): e3000461, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31600191
15.
Directed evolution of a carbonyl reductase LsCR for the enantioselective synthesis of (1S)-2-chloro-1-(3,4-difluorophenyl) ethanol.
Bioorg Chem
; 127: 105991, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35816872
16.
Diterbutyl phthalate attenuates osteoarthritis in ACLT mice via suppressing ERK/c-fos/NFATc1 pathway, and subsequently inhibiting subchondral osteoclast fusion.
Acta Pharmacol Sin
; 43(5): 1299-1310, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34381182
17.
Semirational engineering of an aldo-keto reductase KmAKR for overcoming trade-offs between catalytic activity and thermostability.
Biotechnol Bioeng
; 118(11): 4441-4452, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34374988
18.
Tuning enzymatic properties by protein engineering toward catalytic tetrad of carbonyl reductase.
Biotechnol Bioeng
; 118(12): 4643-4654, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34436762
19.
Tailoring an aldo-keto reductase KmAKR for robust thermostability and catalytic efficiency by stepwise evolution and structure-guided consensus engineering.
Bioorg Chem
; 109: 104712, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33735657
20.
Hb Guangxi [ß65(E9)LysâGlu (AAG>GAG); HBB: c.196A>G]: A Novel ß-Globin Variant.
Hemoglobin
; 45(6): 349-350, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31437061