Detalhe da pesquisa
1.
An anchor-tether 'hindered' HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model.
Br J Anaesth
; 131(4): 745-763, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567808
2.
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.
Proc Natl Acad Sci U S A
; 113(7): 1778-83, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26831078
3.
[18F]Fluoroethyltriazolyl Monocyclam Derivatives as Imaging Probes for the Chemokine Receptor CXCR4.
Molecules
; 24(8)2019 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31022852
4.
Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium.
Proc Natl Acad Sci U S A
; 111(14): E1402-8, 2014 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24706818
5.
Biosynthesis of cell envelope-associated phenolic glycolipids in Mycobacterium marinum.
J Bacteriol
; 197(6): 1040-50, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25561717
6.
Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 59(10): 6521-38, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26239979
7.
Inhibitors selective for mycobacterial versus human proteasomes.
Nature
; 461(7264): 621-6, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19759536
8.
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials.
Proc Natl Acad Sci U S A
; 109(40): 16004-11, 2012 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23012453
9.
Cyanine fluorophore derivatives with enhanced photostability.
Nat Methods
; 9(1): 68-71, 2011 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22081126
10.
The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin.
J Am Soc Nephrol
; 24(8): 1250-61, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23813215
11.
Combinatorial Ubiquitination REal-time PROteolysis (CURE-PROs): A Modular Platform for Generating Reversible, Self-Assembling Bifunctional Targeted Degraders.
J Med Chem
; 67(7): 5473-5501, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38554135
12.
Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice.
Antimicrob Agents Chemother
; 57(10): 5138-40, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23856770
13.
Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells.
Proc Natl Acad Sci U S A
; 107(12): 5477-82, 2010 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20212119
14.
On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis.
Arch Biochem Biophys
; 509(1): 90-9, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21303655
15.
PROTACs: Promising Approaches for Epigenetic Strategies to Overcome Drug Resistance.
Curr Cancer Drug Targets
; 21(4): 306-325, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33535953
16.
Tetrathiomolybdate (TM)-associated copper depletion influences collagen remodeling and immune response in the pre-metastatic niche of breast cancer.
NPJ Breast Cancer
; 7(1): 108, 2021 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426581
17.
Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase .
Biochemistry
; 49(8): 1616-27, 2010 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20078138
18.
Enhanced photostability of cyanine fluorophores across the visible spectrum.
Nat Methods
; 9(5): 428-9, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22543373
19.
Structure-Activity Relationships of Noncovalent Immunoproteasome ß5i-Selective Dipeptides.
J Med Chem
; 63(21): 13103-13123, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33095579
20.
Cooperation between a coenzyme A-independent stand-alone initiation module and an iterative type I polyketide synthase during synthesis of mycobacterial phenolic glycolipids.
J Am Chem Soc
; 131(46): 16744-50, 2009 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19799378