Detalhe da pesquisa
1.
Surveying heterocycles as amide bioisosteres within a series of mGlu7 NAMs: Discovery of VU6019278.
Bioorg Med Chem Lett
; 29(10): 1211-1214, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30910459
2.
Discovery of VU6027459: A First-in-Class Selective and CNS Penetrant mGlu7 Positive Allosteric Modulator Tool Compound.
ACS Med Chem Lett
; 11(9): 1773-1779, 2020 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32944146
3.
Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu7 Negative Allosteric Modulator (NAM) in Vivo Tool Compound: N-(2-(1 H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU6012962).
J Med Chem
; 62(3): 1690-1695, 2019 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30608678