Detalhe da pesquisa
1.
Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling.
Blood
; 143(10): 845-857, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096370
2.
TF-FVIIa PAR2-ß-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice.
Arterioscler Thromb Vasc Biol
; 44(4): 843-865, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38385286
3.
EPCR deficiency ameliorates inflammatory arthritis in mice by suppressing the activation and migration of T cells and dendritic cells.
Rheumatology (Oxford)
; 63(2): 571-580, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37228024
4.
A recombinant signalling-selective activated protein C that lacks anticoagulant activity is efficacious and safe in cutaneous wound preclinical models.
Wound Repair Regen
; 32(1): 90-103, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38155595
5.
Thrombomodulin is essential for maintaining quiescence in vascular endothelial cells.
Proc Natl Acad Sci U S A
; 118(11)2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33836597
6.
Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model.
Int J Mol Sci
; 25(2)2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279255
7.
Tissue factor pathway inhibitor is required for cerebrovascular development in mice.
Blood
; 137(2): 258-268, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32735640
8.
The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse.
Haematologica
; 107(9): 2133-2143, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35142156
9.
Blocking hemophilic arthropathy.
Blood
; 139(18): 2734-2735, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35511191
10.
The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability.
Bioorg Med Chem
; 27(17): 3788-3796, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320211
11.
Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice.
Dev Biol
; 410(2): 190-201, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26746789
12.
Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and ß-Catenin/GSK-3ß Protein Signaling.
J Biol Chem
; 291(8): 4128-43, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26719331
13.
Nogo-B receptor deficiency increases liver X receptor alpha nuclear translocation and hepatic lipogenesis through an adenosine monophosphate-activated protein kinase alpha-dependent pathway.
Hepatology
; 64(5): 1559-1576, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27480224
14.
Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation.
Blood
; 125(8): 1339-48, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25575539
15.
A balance between TFPI and thrombin-mediated platelet activation is required for murine embryonic development.
Blood
; 125(26): 4078-84, 2015 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25954015
16.
EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice.
Blood
; 125(18): 2845-54, 2015 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733582
17.
Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice.
Blood
; 126(21): 2415-23, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26341257
18.
High endogenous activated protein C levels attenuates bleomycin-induced pulmonary fibrosis.
J Cell Mol Med
; 20(11): 2029-2035, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27295971
19.
A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII.
Blood
; 123(24): 3706-13, 2014 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705491
20.
Overexpression of activated protein C hampers bacterial dissemination during pneumococcal pneumonia.
BMC Infect Dis
; 14: 559, 2014 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25366058