Detalhe da pesquisa
1.
Single-domain antibodies reveal unique borrelicidal epitopes on the Lyme disease vaccine antigen, outer surface protein A (OspA).
Infect Immun
; 92(4): e0008424, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38470113
2.
Optimization of a Hydrogen Exchange-Mass Spectrometry Robotic Liquid Handler Using Tracers.
Anal Chem
; 96(4): 1522-1529, 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38237105
3.
Structure of a transmission blocking antibody in complex with Outer surface protein A from the Lyme disease spirochete, Borreliella burgdorferi.
Proteins
; 91(11): 1463-1470, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37455569
4.
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Nat Methods
; 16(7): 595-602, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31249422
5.
Statistical Equivalence Testing of Higher-Order Protein Structures with Differential Hydrogen Exchange-Mass Spectrometry (HX-MS).
Anal Chem
; 93(18): 6980-6988, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33913686
6.
A Structural Variant Approach for Establishing a Detection Limit in Differential Hydrogen Exchange-Mass Spectrometry Measurements.
Anal Chem
; 91(13): 8017-8024, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31099552
7.
Reliable Identification of Significant Differences in Differential Hydrogen Exchange-Mass Spectrometry Measurements Using a Hybrid Significance Testing Approach.
Anal Chem
; 91(13): 8008-8016, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31099554
8.
Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb.
Anal Chem
; 91(11): 7336-7345, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31045344
9.
Quantifying Protection in Disordered Proteins Using Millisecond Hydrogen Exchange-Mass Spectrometry and Peptic Reference Peptides.
Biochemistry
; 56(31): 4064-4072, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28675294
10.
Soft interactions and volume exclusion by polymeric crowders can stabilize or destabilize transient structure in disordered proteins depending on polymer concentration.
Proteins
; 85(8): 1468-1479, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28425679
11.
Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies.
Proteins
; 85(11): 1994-2008, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28718923
12.
Automated Strong Cation-Exchange Cleanup To Remove Macromolecular Crowding Agents for Protein Hydrogen Exchange Mass Spectrometry.
Anal Chem
; 89(2): 1275-1282, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27936623
13.
Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements.
Anal Chem
; 89(17): 8931-8941, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753295
14.
Label-Free, In-Solution Screening of Peptide Libraries for Binding to Protein Targets Using Hydrogen Exchange Mass Spectrometry.
J Am Chem Soc
; 138(4): 1335-43, 2016 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26741284
15.
Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 °C and 25.4 °C for the Fab Fragment of NISTmAb.
J Res Natl Inst Stand Technol
; 124: 1-7, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-34877153
16.
Understanding the effects of site-specific light chain conjugation on antibody structure using hydrogen exchange-mass spectrometry (HX-MS).
J Pharm Sci
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38761863
17.
Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody.
Biochemistry
; 52(19): 3376-89, 2013 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23594236
18.
The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
J Am Chem Soc
; 135(50): 18840-9, 2013 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24313858
19.
Analysis of disordered proteins using a simple apparatus for millisecond quench-flow H/D exchange.
Anal Chem
; 85(10): 5161-8, 2013 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23586525
20.
High-Throughput Epitope Mapping by Hydrogen Exchange-Mass Spectrometry.
J Am Soc Mass Spectrom
; 34(1): 123-127, 2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36449379