Detalhe da pesquisa
1.
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Cell
; 186(14): 3013-3032.e22, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37352855
2.
Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis.
Cell
; 185(17): 3214-3231.e23, 2022 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907404
3.
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Cell
; 159(7): 1563-77, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25525875
4.
Mitochondrial DNA release and sensing in innate immune responses.
Hum Mol Genet
; 33(R1): R80-R91, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38779772
5.
The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature
; 587(7835): 673-677, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911481
6.
NF-κB-Inducing Kinase Governs the Mitochondrial Respiratory Capacity, Differentiation, and Inflammatory Status of Innate Immune Cells.
J Immunol
; 210(8): 1123-1133, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36881877
7.
Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway.
J Immunol
; 210(11): 1761-1770, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37067290
8.
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature
; 569(7758): 718-722, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31118511
9.
Inflammatory and interferon gene expression signatures in patients with mitochondrial disease.
J Transl Med
; 21(1): 331, 2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37208779
10.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
J Immunol
; 206(8): 1890-1900, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33731338
11.
TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection.
J Immunol
; 205(1): 153-167, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404352
12.
Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse.
Neurogenetics
; 22(4): 297-312, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34345994
13.
Neuroimmune mechanisms of cognitive impairment in a mouse model of Gulf War illness.
Brain Behav Immun
; 97: 204-218, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34333111
14.
A virus-acquired host cytokine controls systemic aging by antagonizing apoptosis.
PLoS Biol
; 16(7): e2005796, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30036358
15.
Mitochondrial DNA stress primes the antiviral innate immune response.
Nature
; 520(7548): 553-7, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25642965
16.
Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.
Neurogenetics
; 21(3): 187-203, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342250
17.
Impact of pharmacological agents on mitochondrial function: a growing opportunity?
Biochem Soc Trans
; 47(6): 1757-1772, 2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31696924
18.
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
Nature
; 472(7344): 476-80, 2011 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21525932
19.
MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury.
Am J Physiol Lung Cell Mol Physiol
; 306(7): L604-19, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24487387
20.
3D convolutional neural networks predict cellular metabolic pathway use from fluorescence lifetime decay data.
APL Bioeng
; 8(1): 016112, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38420625