Detalhe da pesquisa
1.
BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.
J Pharmacol Exp Ther
; 357(3): 554-61, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27048659
2.
Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis.
Eur Respir J
; 45(5): 1434-45, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25745043
3.
Induced Syk deletion leads to suppressed allergic responses but has no effect on neutrophil or monocyte migration in vivo.
Eur J Immunol
; 41(11): 3208-18, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21830208
4.
Olodaterol shows anti-fibrotic efficacy in in vitro and in vivo models of pulmonary fibrosis.
Br J Pharmacol
; 174(21): 3848-3864, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28810065
5.
Olodaterol attenuates citric acid-induced cough in naïve and ovalbumin-sensitized and challenged guinea pigs.
PLoS One
; 10(3): e0119953, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25781609
6.
The long-acting ß2 -adrenoceptor agonist olodaterol attenuates pulmonary inflammation.
Br J Pharmacol
; 172(14): 3537-47, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25824824
7.
A novel model of IgE-mediated passive pulmonary anaphylaxis in rats.
PLoS One
; 9(12): e116166, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25541997
8.
Molecular basis for the long duration of action and kinetic selectivity of tiotropium for the muscarinic M3 receptor.
J Med Chem
; 56(21): 8746-56, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24088171
9.
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.
Nat Med
; 18(9): 1401-6, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922409
10.
Syk and Lyn mediate distinct Syk phosphorylation events in FcÉRI-signal transduction: implications for regulation of IgE-mediated degranulation.
Mol Immunol
; 48(1-3): 171-8, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20828828