Detalhe da pesquisa
1.
HSP90 Shapes the Consequences of Human Genetic Variation.
Cell
; 168(5): 856-866.e12, 2017 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215707
2.
Widespread macromolecular interaction perturbations in human genetic disorders.
Cell
; 161(3): 647-660, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25910212
3.
The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy.
Cell
; 158(3): 564-78, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25083868
4.
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers.
Cell
; 150(3): 549-62, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863008
5.
Mitochondrial metabolism promotes adaptation to proteotoxic stress.
Nat Chem Biol
; 15(7): 681-689, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31133756
6.
Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress.
Nat Chem Biol
; 15(7): 757, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31164776
7.
Exploring boron applications in modern agriculture: A structure-activity relationship study of a novel series of multi-substitution benzoxaboroles for identification of potential fungicides.
Bioorg Med Chem Lett
; 43: 128089, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964438
8.
Enhanced Efflux Pump Expression in Candida Mutants Results in Decreased Manogepix Susceptibility.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32179530
9.
Antifungal Activity of Gepinacin Scaffold Glycosylphosphatidylinositol Anchor Biosynthesis Inhibitors with Improved Metabolic Stability.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661007
10.
Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy.
Nat Chem Biol
; 14(2): 135-141, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29227471
11.
FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome.
Proc Natl Acad Sci U S A
; 114(52): E11313-E11322, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229832
12.
Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.
Proc Natl Acad Sci U S A
; 114(2): 382-387, 2017 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28028240
13.
Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation.
J Nat Prod
; 81(4): 825-837, 2018 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29537263
14.
Nontoxic antimicrobials that evade drug resistance.
Nat Chem Biol
; 11(7): 481-7, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26030729
15.
HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models.
Proc Natl Acad Sci U S A
; 111(51): 18297-302, 2014 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25489079
16.
Calcineurin determines toxic versus beneficial responses to α-synuclein.
Proc Natl Acad Sci U S A
; 111(34): E3544-52, 2014 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122673
17.
Synthesis of Aza-Rocaglates via ESIPT-Mediated (3+2) Photocycloaddition.
Chemistry
; 22(34): 12006-10, 2016 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27338157
18.
Fitness trade-offs restrict the evolution of resistance to amphotericin B.
PLoS Biol
; 11(10): e1001692, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24204207
19.
Biomimetic kinetic resolution: highly enantio- and diastereoselective transfer hydrogenation of aglain ketones to access flavagline natural products.
J Am Chem Soc
; 137(1): 525-30, 2015 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25514979
20.
HSP90 and the chaperoning of cancer.
Nat Rev Cancer
; 5(10): 761-72, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16175177