Detalhe da pesquisa
1.
Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis.
Antimicrob Agents Chemother
; 67(4): e0142522, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36920244
2.
Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy.
Antimicrob Agents Chemother
; 66(7): e0001722, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35703552
3.
Complementary Nonsputum Diagnostic Testing for Tuberculosis in People with HIV Using Oral Swab PCR and Urine Lipoarabinomannan Detection.
J Clin Microbiol
; 60(8): e0043122, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35913145
4.
P-Glycoprotein-Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium.
J Infect Dis
; 220(7): 1188-1198, 2019 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31180118
5.
Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis.
J Infect Dis
; 219(9): 1464-1473, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423128
6.
Treatment with Bumped Kinase Inhibitor 1294 Is Safe and Leads to Significant Protection against Abortion and Vertical Transmission in Sheep Experimentally Infected with Toxoplasma gondii during Pregnancy.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31061151
7.
Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis.
Antimicrob Agents Chemother
; 62(7)2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661877
8.
Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection.
J Infect Dis
; 216(1): 55-63, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28541457
9.
Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
J Infect Dis
; 215(8): 1275-1284, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28329187
10.
5-Aminopyrazole-4-Carboxamide-Based Compounds Prevent the Growth of Cryptosporidium parvum.
Antimicrob Agents Chemother
; 61(8)2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533246
11.
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer.
bioRxiv
; 2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37461469
12.
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer.
Mol Cancer Ther
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38507737
13.
In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts.
Int J Parasitol Drugs Drug Resist
; 16: 90-101, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34030110
14.
Pyrrolopyrimidine Bumped Kinase Inhibitors for the Treatment of Cryptosporidiosis.
ACS Infect Dis
; 7(5): 1200-1207, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33565854
15.
Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo.
Int J Parasitol Drugs Drug Resist
; 17: 92-106, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34482255
16.
A short-term treatment with BKI-1294 does not protect foetuses from sheep experimentally infected with Neospora caninum tachyzoites during pregnancy.
Int J Parasitol Drugs Drug Resist
; 17: 176-185, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34655903
17.
Repurposing Infectious Disease Hits as Anti-Cryptosporidium Leads.
ACS Infect Dis
; 7(5): 1275-1282, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740373
18.
One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases.
Vet Parasitol
; 289: 109336, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33418437
19.
Reduced treatment frequencies with bumped kinase inhibitor 1369 are effective against porcine cystoisosporosis.
Int J Parasitol Drugs Drug Resist
; 14: 37-45, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32861205
20.
Comparative assessment of the effects of bumped kinase inhibitors on early zebrafish embryo development and pregnancy in mice.
Int J Antimicrob Agents
; 56(3): 106099, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32707170