Detalhe da pesquisa
1.
Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles.
Bioorg Med Chem Lett
; 18(6): 2006-12, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18313920
2.
Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-3-hydroxy-4-(spiro[chromene-2,4'-piperidine]-4-yl) benzamide (ADL5747).
J Med Chem
; 52(18): 5685-702, 2009 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19694468
3.
Potent, orally bioavailable delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (ADL5859).
J Med Chem
; 51(19): 5893-6, 2008 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18788723