Detalhe da pesquisa
1.
Adenosine A2A receptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis.
FASEB J
; 32(7): 3487-3501, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29394106
2.
Adenosine A2a Receptor Blockade Diminishes Wnt/ß-Catenin Signaling in a Murine Model of Bleomycin-Induced Dermal Fibrosis.
Am J Pathol
; 187(9): 1935-1944, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28667836
3.
Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis.
FASEB J
; 30(11): 3835-3844, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27502509
4.
Ticagrelor regulates osteoblast and osteoclast function and promotes bone formation in vivo via an adenosine-dependent mechanism.
FASEB J
; 30(11): 3887-3900, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27511945
5.
Netrin-1 is highly expressed and required in inflammatory infiltrates in wear particle-induced osteolysis.
Ann Rheum Dis
; 75(9): 1706-13, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26452536
6.
Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.
FASEB J
; 29(4): 1577-90, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25573752
7.
Adenosine A2B receptors play an important role in bone homeostasis.
Purinergic Signal
; 12(3): 537-47, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27289226
8.
Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.
Am J Pathol
; 183(6): 1740-1746, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24266925
9.
Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma.
FASEB J
; 27(9): 3446-54, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23682121
10.
Adenosine A(2A) receptor ligation inhibits osteoclast formation.
Am J Pathol
; 180(2): 775-86, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22138579
11.
Restraint stress fails to modulate cutaneous hypersensitivity responses in mice lacking the adenosine A1 receptor.
Purinergic Signal
; 7(1): 47-56, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21484096
12.
Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine.
Am J Pathol
; 172(6): 1675-82, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18467695
13.
Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
FASEB J
; 22(7): 2263-72, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18263696
14.
Tenofovir Causes Bone Loss via Decreased Bone Formation and Increased Bone Resorption, Which Can Be Counteracted by Dipyridamole in Mice.
J Bone Miner Res
; 34(5): 923-938, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30645771
15.
Bone regeneration in critical bone defects using three-dimensionally printed ß-tricalcium phosphate/hydroxyapatite scaffolds is enhanced by coating scaffolds with either dipyridamole or BMP-2.
J Biomed Mater Res B Appl Biomater
; 105(2): 366-375, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26513656
16.
The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.
PLoS One
; 12(11): e0188135, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29145453
17.
Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression.
Nat Commun
; 8: 15019, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28492224
18.
Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor.
Arthritis Rheumatol
; 67(3): 849-55, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533750
19.
Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.
Arthritis Res Ther
; 17: 249, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26370839
20.
Rolofylline, an adenosine A1 receptor antagonist, inhibits osteoclast differentiation as an inverse agonist.
Br J Pharmacol
; 170(6): 1167-76, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23962057