Detalhe da pesquisa
1.
Ceramide levels in blood plasma correlate with major depressive disorder severity and its neutralization abrogates depressive behavior in mice.
J Biol Chem
; 298(8): 102185, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753355
2.
Role of Tyrosine Nitrosylation in Stress-Induced Major Depressive Disorder: Mechanisms and Implications.
Int J Mol Sci
; 24(19)2023 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37834072
3.
Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis.
J Biol Chem
; 296: 100650, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33839155
4.
Molecular targets of endothelial phosphatidic acid regulating major depressive disorder.
J Neurochem
; 163(4): 357-369, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36227646
5.
Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2.
J Biol Chem
; 295(45): 15174-15182, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32917722
6.
Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections.
Infect Immun
; 89(2)2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139382
7.
Signalling Effects Induced by Acid Ceramidase in Human Epithelial Or Leukemic Cell Lines.
Cell Physiol Biochem
; 52(5): 1092-1102, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30977990
8.
Inhibition of PI-3-K and AKT Amplifies Kv1.3 Inhibitor-Induced Death of Human T Leukemia Cells.
Cell Physiol Biochem
; 53(S1): 1-10, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31804046
9.
Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs has no Adverse Side Effects.
Cell Physiol Biochem
; 53(6): 1015-1028, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31854953
10.
Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide.
Mol Psychiatry
; 23(12): 2324-2346, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30038230
11.
Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide.
Infect Immun
; 86(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29084896
12.
Pulmonary infection of cystic fibrosis mice with Staphylococcus aureus requires expression of α-toxin.
Biol Chem
; 399(10): 1203-1213, 2018 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29613852
13.
Glucosylceramide Critically Contributes to the Host Defense of Cystic Fibrosis Lungs.
Cell Physiol Biochem
; 41(3): 1208-1218, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28427052
14.
Regulation of Neuronal Stem Cell Proliferation in the Hippocampus by Endothelial Ceramide.
Cell Physiol Biochem
; 39(2): 790-801, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27475812
15.
Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis.
Cell Physiol Biochem
; 38(1): 1-14, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26741636
16.
Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System.
Neurosignals
; 24(1): 48-58, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27398923
17.
Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression.
Neurosignals
; 23(1): 84-92, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26682751
18.
Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functions.
J Mol Med (Berl)
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38780771
19.
Simultaneous targeting of mitochondrial Kv1.3 and lysosomal acid sphingomyelinase amplifies killing of pancreatic ductal adenocarcinoma cells in vitro and in vivo.
J Mol Med (Berl)
; 101(3): 295-310, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790532
20.
Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease.
Front Endocrinol (Lausanne)
; 14: 1211473, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37435490