Detalhe da pesquisa
1.
Transgenic ferret models define pulmonary ionocyte diversity and function.
Nature
; 621(7980): 857-867, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37730992
2.
Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus.
Mol Ther
; 30(1): 223-237, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33794364
3.
Airway Gland Structure and Function.
Physiol Rev
; 95(4): 1241-319, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26336032
4.
Granule-stored MUC5B mucins are packed by the non-covalent formation of N-terminal head-to-head tetramers.
J Biol Chem
; 293(15): 5746-5754, 2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29440393
5.
The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin.
Biochem Biophys Res Commun
; 492(3): 331-337, 2017 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28859985
6.
Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.
Am J Respir Cell Mol Biol
; 54(4): 469-81, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334941
7.
Mucociliary clearance and submucosal gland secretion in the ex vivo ferret trachea.
Am J Physiol Lung Cell Mol Physiol
; 307(1): L83-93, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24793168
8.
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.
Proc Natl Acad Sci U S A
; 108(46): 18843-8, 2011 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21976485
9.
How the sweat gland reveals levels of CFTR activity.
J Cyst Fibros
; 21(3): 396-406, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35184981
10.
Variation in CFTR-dependent 'ß-sweating' among healthy adults.
PLoS One
; 17(3): e0265432, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35312728
11.
Properties of substance P-stimulated mucus secretion from porcine tracheal submucosal glands.
Am J Physiol Lung Cell Mol Physiol
; 300(3): L370-9, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21131402
12.
Combined agonists act synergistically to increase mucociliary clearance in a cystic fibrosis airway model.
Sci Rep
; 11(1): 18828, 2021 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34552115
13.
Mucus secretion from individual submucosal glands of the ferret trachea.
Am J Physiol Lung Cell Mol Physiol
; 299(1): L124-36, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20435689
14.
Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis.
J Clin Invest
; 117(10): 3118-27, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17853942
15.
Measuring mucociliary transport and mucus properties in multiple regions of airway epithelial surfaces helps clarify cystic fibrosis defects.
Am J Respir Crit Care Med
; 190(4): 364-5, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25127304
16.
High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia.
Cell Stem Cell
; 26(2): 161-171.e4, 2020 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31839569
17.
Ivacaftor restores CFTR-dependent sweat gland fluid secretion in cystic fibrosis subjects with S945L alleles.
J Cyst Fibros
; 17(2): 179-185, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29279204
18.
Progress in understanding mucus abnormalities in cystic fibrosis airways.
J Cyst Fibros
; 17(2S): S35-S39, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28951068
19.
Sweat rate analysis of ivacaftor potentiation of CFTR in non-CF adults.
Sci Rep
; 8(1): 16233, 2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30389955
20.
Parasympathetic control of airway submucosal glands: central reflexes and the airway intrinsic nervous system.
Auton Neurosci
; 133(1): 35-54, 2007 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17350348