Detalhe da pesquisa
1.
Identification of structural-kinetic and structural-thermodynamic relationships for thrombin inhibitors.
Biochemistry
; 52(4): 613-26, 2013 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23290007
2.
Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic Dyad.
J Med Chem
; 59(21): 9743-9759, 2016 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27726357
3.
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.
J Med Chem
; 57(5): 1952-63, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24131104
4.
Resolution of the interaction mechanisms and characteristics of non-nucleoside inhibitors of hepatitis C virus polymerase.
Antiviral Res
; 97(3): 356-68, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23305851
5.
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.
J Med Chem
; 56(6): 2270-82, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23409936
6.
Experimental validation of a fragment library for lead discovery using SPR biosensor technology.
J Biomol Screen
; 16(1): 15-25, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21149860
7.
Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data.
PLoS One
; 4(6): e6057, 2009 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19557126