Detalhe da pesquisa
1.
Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Cell
; 178(4): 993-1003.e12, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353218
2.
Structural Basis for High-Affinity Trapping of the NaV1.7 Channel in Its Resting State by Tarantula Toxin.
Mol Cell
; 81(1): 38-48.e4, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33232657
3.
Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel NaV1.7.
Proc Natl Acad Sci U S A
; 120(14): e2219624120, 2023 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996107
4.
The conformational cycle of a prototypical voltage-gated sodium channel.
Nat Chem Biol
; 16(12): 1314-1320, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199904
5.
The chemical basis for electrical signaling.
Nat Chem Biol
; 13(5): 455-463, 2017 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28406893
6.
Crystal structure of a nitrate/nitrite exchanger.
Nature
; 497(7451): 647-51, 2013 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665960
7.
Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin.
Nat Commun
; 15(1): 2306, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38485923
8.
Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.
J Gen Physiol
; 155(12)2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37903281
9.
Druggability of Voltage-Gated Sodium Channels-Exploring Old and New Drug Receptor Sites.
Front Pharmacol
; 13: 858348, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35370700
10.
Structures of Mycobacterium tuberculosis DosR and DosR-DNA complex involved in gene activation during adaptation to hypoxic latency.
J Mol Biol
; 354(3): 630-41, 2005 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16246368
11.
Crystal structure of an IdeR-DNA complex reveals a conformational change in activated IdeR for base-specific interactions.
J Mol Biol
; 342(4): 1155-69, 2004 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15351642
12.
Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase.
Chem Biol
; 9(11): 1189-97, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12445769
13.
Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.
Nat Commun
; 5: 4521, 2014 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25088546
14.
Phasing electron diffraction data by molecular replacement: strategy for structure determination and refinement.
Methods Mol Biol
; 955: 243-72, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23132065
15.
Fragment-based phase extension for three-dimensional structure determination of membrane proteins by electron crystallography.
Structure
; 19(7): 976-87, 2011 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21742264
16.
Advances in structural and functional analysis of membrane proteins by electron crystallography.
Structure
; 19(10): 1381-93, 2011 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22000511
17.
Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.
Structure
; 18(11): 1512-21, 2010 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21070950
18.
Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation.
J Mol Biol
; 378(1): 227-42, 2008 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18353359
19.
Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis.
Biochemistry
; 46(2): 436-47, 2007 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17209554
20.
An improved protocol for rapid freezing of protein samples for long-term storage.
Acta Crystallogr D Biol Crystallogr
; 60(Pt 1): 203-4, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14684931