Detalhe da pesquisa
1.
A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins.
Nat Chem Biol
; 19(10): 1246-1255, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37592157
2.
Structural basis for Lewis antigen synthesis by the α1,3-fucosyltransferase FUT9.
Nat Chem Biol
; 19(8): 1022-1030, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37202521
3.
Characterization of a new family of 6-sulfo-N-acetylglucosaminidases.
J Biol Chem
; 299(10): 105214, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37660924
4.
Influenza virus and pneumococcal neuraminidases enhance catalysis by similar yet distinct sialic acid-binding strategies.
J Biol Chem
; 299(2): 102891, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36634846
5.
Ligand-Directed Chemistry on Glycoside Hydrolases - A Proof of Concept Study.
Chembiochem
; 24(23): e202300480, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37715738
6.
Branched montbretin A mimics allow derivatisation and potent amylase inhibition.
Org Biomol Chem
; 21(39): 7977-7983, 2023 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751159
7.
Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors.
Angew Chem Int Ed Engl
; 62(21): e202301258, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36940280
8.
Mammalian sialyltransferases allow efficient Escherichia coli-based production of mucin-type O-glycoproteins but can also transfer Kdo.
Glycobiology
; 32(5): 429-440, 2022 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34939113
9.
Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases.
Glycobiology
; 32(2): 162-170, 2022 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34792586
10.
Design of the Recombinant Influenza Neuraminidase Antigen Is Crucial for Its Biochemical Properties and Protective Efficacy.
J Virol
; 95(24): e0116021, 2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34613807
11.
Observing cellulose biosynthesis and membrane translocation in crystallo.
Nature
; 531(7594): 329-34, 2016 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26958837
12.
Pharmacological Chaperones for GCase that Switch Conformation with pH Enhance Enzyme Levels in Gaucher Animal Models.
Angew Chem Int Ed Engl
; 61(38): e202207974, 2022 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35864061
13.
Toward universal donor blood: Enzymatic conversion of A and B to O type.
J Biol Chem
; 295(2): 325-334, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31792054
14.
Discovery of UDP-Glycosyltransferases and BAHD-Acyltransferases Involved in the Biosynthesis of the Antidiabetic Plant Metabolite Montbretin A.
Plant Cell
; 30(8): 1864-1886, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29967287
15.
Discovery of ß-N-acetylglucosaminidases from screening metagenomic libraries and their use as thioglycoligase mutants.
Org Biomol Chem
; 19(41): 9068-9075, 2021 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34622263
16.
Synthesis and evaluation of sensitive coumarin-based fluorogenic substrates for discovery of α-N-acetyl galactosaminidases through droplet-based screening.
Org Biomol Chem
; 19(4): 789-793, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33411870
17.
Oversized galactosides as a probe for conformational dynamics in LacY.
Proc Natl Acad Sci U S A
; 115(16): 4146-4151, 2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29602806
18.
Chemoenzymatic Synthesis of Chito-oligosaccharides with Alternating N-d-Acetylglucosamine and d-Glucosamine.
Biochemistry
; 59(48): 4581-4590, 2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33213137
19.
Prospecting for microbial α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase.
J Biol Chem
; 294(44): 16400-16415, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31530641
20.
High-Throughput Generation of Product Profiles for Arabinoxylan-Active Enzymes from Metagenomes.
Appl Environ Microbiol
; 86(23)2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32948521