Detalhe da pesquisa
1.
Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide.
Bioorg Med Chem Lett
; 26(20): 5103-5109, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27614414
2.
Knockdown of ß-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo.
Mol Ther
; 22(1): 92-101, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24089139
3.
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.
Neuro Oncol
; 9(3): 259-70, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17522330
4.
Antitumor activity of TGF-beta inhibitor is dependent on the microenvironment.
Anticancer Res
; 27(6B): 4149-57, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18229422
5.
Basic mechanisms responsible for osteolytic and osteoblastic bone metastases.
Clin Cancer Res
; 12(20 Pt 2): 6213s-6216s, 2006 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17062703
6.
SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo.
Cancer Res
; 64(21): 7954-61, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15520202
7.
Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.
PLoS One
; 4(4): e5275, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19357790
8.
Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness.
Mol Pharmacol
; 72(1): 152-61, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17400764
9.
Peptidic 1-cyanopyrrolidines: synthesis and SAR of a series of potent, selective cathepsin inhibitors.
Bioorg Med Chem
; 10(10): 3277-84, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12150873