1.
Bioorg Med Chem Lett
; 18(1): 90-4, 2008 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18032036
RESUMO
Optimisation of a series of oxazole diketopiperazines has led to the discovery of a very potent and selective oxytocin antagonist GSK221149A. GSK221149A has been shown to inhibit oxytocin-induced uterine contractions in the anaesthetised rat.