Detalhe da pesquisa
1.
Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis.
Nucleic Acids Res
; 49(5): 2973-2984, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619565
2.
High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design.
Biochem Biophys Res Commun
; 534: 330-336, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33272565
3.
A Rationale for Drug Design Provided by Co-Crystal Structure of IC261 in Complex with Tubulin.
Molecules
; 26(4)2021 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579052
4.
Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain.
Angew Chem Int Ed Engl
; 60(16): 8760-8765, 2021 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33511756
5.
Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design.
Biochem Biophys Res Commun
; 2020 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32085900
6.
Lysophosphatidic Acid Receptor 5 (LPAR5) Plays a Significance Role in Papillary Thyroid Cancer via Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (mTOR) Pathway.
Med Sci Monit
; 26: e919820, 2020 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31902939
7.
Growth-associated protein 43 promotes thyroid cancer cell lines progression via epithelial-mesenchymal transition.
J Cell Mol Med
; 23(12): 7974-7984, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31568662
8.
Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
Biochem Biophys Res Commun
; 511(2): 381-386, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30803758
9.
Structure of a benzylidene derivative of 9(10H)-anthracenone in complex with tubulin provides a rationale for drug design.
Biochem Biophys Res Commun
; 495(1): 185-188, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29102632
10.
Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design.
Biochem Biophys Res Commun
; 493(1): 718-722, 2017 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28864414
11.
[Effects of tree species on polysaccharides content of epiphytic Dendrobium officinale].
Zhongguo Zhong Yao Za Zhi
; 39(21): 4222-4, 2014 Nov.
Artigo
em Zh
| MEDLINE | ID: mdl-25775797
12.
Emerging trends in small molecule inhibitors targeting aldosterone synthase: A new paradigm in cardiovascular disease treatment.
Eur J Med Chem
; 274: 116521, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38820853
13.
Development and therapeutic implications of small molecular inhibitors that target calcium-related channels in tumor treatment.
Drug Discov Today
; 29(6): 103995, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38670255
14.
The relationship between long non-coding gene CASC21 polymorphisms and cervical cancer.
Cancer Biol Ther
; 25(1): 2322207, 2024 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38465665
15.
Current advances and development strategies of targeting son of sevenless 1 (SOS1) in drug discovery.
Eur J Med Chem
; 268: 116282, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38430853
16.
Target proteins-regulated DNA nanomachine-electroactive substance complexes enable separation-free electrochemical detection of clinical exosome.
Biosens Bioelectron
; 256: 116273, 2024 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38621341
17.
Self-Assembled DNA Machine and Selective Complexation Recognition Enable Rapid Homogeneous Portable Quantification of Lung Cancer CTCs.
Research (Wash D C)
; 7: 0352, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38711475
18.
Biomolecules-mediated electrochemical signals of Cu2+: Y-DNA nanomachines enable homogeneous rapid one-step assay of lung cancer circulating tumor cells.
Biosens Bioelectron
; 249: 116030, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38241796
19.
Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFRL858R/T790M/ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers.
J Med Chem
; 67(4): 2777-2801, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38323982
20.
Single-Cell Liquid Biopsy of Lung Cancer: Ultra-Simplified Efficient Enrichment of Circulating Tumor Cells and Hand-Held Fluorometer Portable Testing.
ACS Nano
; 18(6): 5017-5028, 2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305181