RESUMO
The magnetic resonance imaging (MRI) findings in 2 cases of ovarian cancer arising in an endometrioma are presented. In both cases, the cancer was evident as an enhancing mass within a blood-filled adnexal cyst. The MRI findings of an enhancing mass within a blood-filled adnexal cyst should prompt consideration of ovarian cancer arising in an endometrioma, facilitating recognition of a superimposed malignancy and potentially allowing for earlier and more efficacious treatment.
Assuntos
Endometriose/patologia , Imageamento por Ressonância Magnética , Cistos Ovarianos/patologia , Neoplasias Ovarianas/patologia , Adenocarcinoma de Células Claras/patologia , Adulto , Carcinoma/patologia , Meios de Contraste , Feminino , Humanos , Aumento da Imagem , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
Functional analysis of a genome requires accurate gene structure information and a complete gene inventory. A dual experimental strategy was used to verify and correct the initial genome sequence annotation of the reference plant Arabidopsis. Sequencing full-length cDNAs and hybridizations using RNA populations from various tissues to a set of high-density oligonucleotide arrays spanning the entire genome allowed the accurate annotation of thousands of gene structures. We identified 5817 novel transcription units, including a substantial amount of antisense gene transcription, and 40 genes within the genetically defined centromeres. This approach resulted in completion of approximately 30% of the Arabidopsis ORFeome as a resource for global functional experimentation of the plant proteome.