Detalhe da pesquisa
1.
An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.
Cell
; 175(2): 530-543.e24, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30220458
2.
DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis.
Nat Chem Biol
; 13(1): 46-53, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27820798
3.
Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity.
J Biol Chem
; 290(17): 11008-20, 2015 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25759383
4.
A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity.
Nat Chem Biol
; 10(8): 656-63, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997602
5.
Preclinical Development of PNT6555, a Boronic Acid-Based, Fibroblast Activation Protein-α (FAP)-Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors.
J Nucl Med
; 65(1): 100-108, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050111
6.
4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities.
Bioorg Med Chem Lett
; 22(17): 5536-40, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853995
7.
Dipeptidyl Peptidase Inhibition Enhances CD8 T Cell Recruitment and Activates Intrahepatic Inflammasome in a Murine Model of Hepatocellular Carcinoma.
Cancers (Basel)
; 13(21)2021 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34771657
8.
Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice.
Mol Metab
; 19: 65-74, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30477988
9.
Synthesis and characterization of constrained peptidomimetic dipeptidyl peptidase IV inhibitors: amino-lactam boroalanines.
J Med Chem
; 50(10): 2391-8, 2007 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-17458948
10.
Human FGF-21 Is a Substrate of Fibroblast Activation Protein.
PLoS One
; 11(3): e0151269, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26962859
11.
Sphingosine kinase 1 isoform-specific interactions in breast cancer.
Mol Endocrinol
; 28(11): 1899-915, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25216046
12.
A pan inhibitor of DASH family enzymes induces immunogenic modulation and sensitizes murine and human carcinoma cells to antigen-specific cytotoxic T lymphocyte killing: implications for combination therapy with cancer vaccines.
Vaccine
; 32(26): 3223-31, 2014 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24731809
13.
Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.
J Med Chem
; 56(9): 3467-77, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23594271
14.
A general method for making peptide therapeutics resistant to serine protease degradation: application to dipeptidyl peptidase IV substrates.
J Med Chem
; 56(21): 8339-51, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24044354
15.
A pan-inhibitor of DASH family enzymes induces immune-mediated regression of murine sarcoma and is a potent adjuvant to dendritic cell vaccination and adoptive T-cell therapy.
J Immunother
; 36(8): 400-11, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23994886
16.
Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.
FEBS Open Bio
; 4: 43-54, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24371721
17.
Pro-soft Val-boroPro: a strategy for enhancing in vivo performance of boronic acid inhibitors of serine proteases.
J Med Chem
; 54(7): 2022-8, 2011 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21388136
18.
Chemical and biological evaluation of dipeptidyl boronic acid proteasome inhibitors for use in prodrugs and pro-soft drugs targeting solid tumors.
J Med Chem
; 54(13): 4365-77, 2011 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21634429
19.
Microscopic acid-base equilibra of alanyl-boroAlanine.
Adv Exp Med Biol
; 524: 333-8, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12675255
20.
Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety.
J Med Chem
; 51(19): 6005-13, 2008 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18783201