Detalhe da pesquisa
1.
Multiplexed in-situ mutagenesis driven by a dCas12a-based dual-function base editor.
Nucleic Acids Res
; 52(8): 4739-4755, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38567723
2.
CRISPR-dCas12a-mediated genetic circuit cascades for multiplexed pathway optimization.
Nat Chem Biol
; 19(3): 367-377, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36646959
3.
A pathway independent multi-modular ordered control system based on thermosensors and CRISPRi improves bioproduction in Bacillus subtilis.
Nucleic Acids Res
; 50(11): 6587-6600, 2022 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35670665
4.
Combinatorial metabolic engineering enables high yield production of α-arbutin from sucrose by biocatalysis.
Appl Microbiol Biotechnol
; 107(9): 2897-2910, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37000229
5.
Combinatorial pathway engineering of Bacillus subtilis for production of structurally defined and homogeneous chitooligosaccharides.
Metab Eng
; 70: 55-66, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35033656
6.
Design of a programmable biosensor-CRISPRi genetic circuits for dynamic and autonomous dual-control of metabolic flux in Bacillus subtilis.
Nucleic Acids Res
; 48(2): 996-1009, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31799627
7.
Synthetic metabolic channel by functional membrane microdomains for compartmentalized flux control.
Metab Eng
; 59: 106-118, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105784
8.
CAMERS-B: CRISPR/Cpf1 assisted multiple-genes editing and regulation system for Bacillus subtilis.
Biotechnol Bioeng
; 117(6): 1817-1825, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32129468
9.
Enzyme assembly guided by SPFH-induced functional inclusion bodies for enhanced cascade biocatalysis.
Biotechnol Bioeng
; 117(5): 1446-1457, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32043560
10.
CRISPRi allows optimal temporal control of N-acetylglucosamine bioproduction by a dynamic coordination of glucose and xylose metabolism in Bacillus subtilis.
Metab Eng
; 49: 232-241, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30176395
11.
Advances and prospects of Bacillus subtilis cellular factories: From rational design to industrial applications.
Metab Eng
; 50: 109-121, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29775652
12.
Engineering Redox Cofactor Balance for Improved 5-Methyltetrahydrofolate Production in Escherichia coli.
J Agric Food Chem
; 72(17): 9974-9983, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38625685
13.
A New-Generation Base Editor with an Expanded Editing Window for Microbial Cell Evolution In Vivo Based on CRISPRâCas12b Engineering.
Adv Sci (Weinh)
; 11(22): e2309767, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602436
14.
Facilitating stable gene integration expression and copy number amplification in Bacillus subtilis through a reversible homologous recombination switch.
Synth Syst Biotechnol
; 9(3): 577-585, 2024 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-38708056
15.
Directed evolution of diacetylchitobiose deacetylase via high-throughput droplet sorting with a novel, bacteria-based biosensor.
Biosens Bioelectron
; 219: 114818, 2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327560
16.
Efficient Synthesis of Limonene in Saccharomyces cerevisiae Using Combinatorial Metabolic Engineering Strategies.
J Agric Food Chem
; 71(20): 7752-7764, 2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37189018
17.
Heterologous Single-Strand DNA-Annealing and Binding Protein Enhance CRISPR-Based Genome Editing Efficiency in Komagataella phaffii.
ACS Synth Biol
; 12(11): 3443-3453, 2023 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37881961
18.
Efficient Protein Expression and Biosynthetic Gene Cluster Regulation in Bacillus subtilis Driven by a T7-BOOST System.
ACS Synth Biol
; 12(11): 3328-3339, 2023 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37885173
19.
ATP-Binding Cassette Exporter PDR11-Mediated Terpenoid Secretion in Engineered Yeast.
ACS Synth Biol
; 12(4): 1146-1153, 2023 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014059
20.
Refactoring transcription factors for metabolic engineering.
Biotechnol Adv
; 57: 107935, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271945